The former Real Madrid defender was playing for Sevilla in a league match they lost 2-1 against Real Sociedad.
But while Sevilla had two players sent off in the match, it was Ramos' dismissal that proved to be somewhat bizarre.
With Real Sociedad trying to close out their 2-1 lead, frustrations were boiling over in the Sevilla side with Ramos picking up a second booking for a foul on Brais Mendez.
After furious appeals, the referee consulted VAR and rescinded the second yellow card - only to then show him a straight-red card instead.
That decision left players bemused, with Jesus Navas also being sent off to leave Sevilla with just nine men on the pitch in the closing minutes of the game.
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That red card was Ramos' 29th of his career, but even for him, the circumstances of this dismissal were bizarre.
Ramos rejoined his boyhood club over the summer after 18 years away following the end of his contract at Paris Saint-Germain.
However, things haven't gone too well for last season's Europa League winners with Sevilla currently sitting 15th in La Liga with just two league wins from 13 matches.
Ramos is one of the most decorated players in football history having won seven league titles, four Champions Leagues, three domestic cups and four Club World Cups.
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He also picked up a staggering 180 caps for Spain that saw him win two European Championships and a World Cup.