Udinese vs. Inter Milan (Saturday, 2.00pm)
After derby defeat stopped them topping the Serie A standings, Inter Milan will attempt to bounce back immediately when they visit Udinese on Saturday.
Last week, Inter were beaten by old foes AC Milan, while their high-flying hosts saw an unbeaten record ended in Rome.
We say: Udinese 1-2 Inter Milan
Even though Udinese have become a tougher proposition since the back end of last season, Inter must surely post their first away win of the season on Saturday.
The Scudetto holders are going through a sticky patch, but their class will shine through and prove sufficient to secure maximum points.
Genoa vs. Juventus (Saturday, 5.00pm)
Clean-sheet specialists Juventus will aim to continue their undefeated start to the season on Saturday, as they visit Genoa at Stadio Luigi Ferraris.
Juve are the only team throughout Europe's top five leagues yet to concede a league goal this season, while their hosts were beaten in Serie A last week before losing a Coppa Italia derby.
We say: Genoa 0-1 Juventus
Neither side is prolific, so this meeting of two up-and-coming coaches could be a tactical affair decided by just one goal.
Given the depth of their resources following a summer of spending, Juventus should finally end their Serie A drought, consigning Genoa to a third straight defeat.
Bologna vs. Atalanta (Saturday, 7.45pm)
Seeking their fourth straight win over Atalanta BC in Serie A, Bologna will welcome La Dea to Stadio Dall'Ara on Saturday evening.
Across all competitions, the hosts have drawn each of their last six home matches, but they will be aiming for back-to-back wins this weekend.
We say: Bologna 1-1 Atalanta BC
Bologna could be bound for a remarkable seventh successive home draw, as they are set to score against hit-and-miss Atalanta but are also likely to be caught out at the other end.
The teams finished side-by-side in Serie A last season, and for all La Dea's individual quality, the Europa League winners tend to struggle on the road.