Uruguay vs. Panama (Saturday, 9.00pm)
Following the cancellation of Uruguay's friendly with Jamaica by CONCACAF, the South Americans will instead host Panama at the Estadio Centenario on Saturday.
It will be the third and final friendly of the June internationals for the hosts, whilst the visitors make the trip during a strange week of fixtures involving friendlies and the CONCACAF Nations League.
We say: Uruguay 3-0 Panama
Given the circumstances involving Panama and the little amount of time between their fixtures, this should be a comfortable victory for the hosts on Saturday.
Uruguay are in excellent form and would be expected to win against Panama regardless, but in this situation, they will be expected to come out with a comprehensive victory by a relatively wide margin.
Ecuador vs. Mali (Sunday, 12.30am)
The Fort Lauderdale Stadium plays host to a thrilling international friendly fixture as Ecuador and Cape Verde go head to head on Saturday.
With their Africa Cup of Nations qualification game against Eswatini on the horizon, victory this weekend will serve as a morale booster for the Blue Sharks who are eyeing a second consecutive AFCON appearance.
We say: Ecuador 2-1 Cape Verde
With their AFCON qualifying game against Eswatini just around the corner, we expect Cape Verde to name a weakened and reshuffled side in this one. Ecuador, who are 25 places higher in the latest FIFA World Rankings, boast a superior and more experienced squad and we predict they will come out victorious.