The duo played alongside each other at Palermo, joined by a certain Italian international Andrea Belotti in attack, firing the club to promotion to Serie A in 2014.
The three of them were managed by former AC Milan madman Gennaro Gattuso and scored a combined 26 goals, helped by ex-Hull striker Abel Hernandez who bagged a further 14.
Lafferty's spell in Italy was short-lived, however, and he was sold after just one season despite their promotion, failing to get his opportunity in the top-flight.
You may be thinking that he was let go because he wasn't good. Nope.
In actual fact, he outscored both Dybala, currently at Juventus, and Torino striker Belotti, bagging 11 league goals in Sicily.
The problem, in the end, was that he actually scored too much - off the pitch, that is. Apparently.
Palermo's owner, Maurizio Zamparini, said in 2014: "He is an out-of-control womanizer, an Irishman without rules.
"He is someone who disappears for a week and goes on the hunt for women in Milan."
Lafferty, though, is a happily married man, who welcomed a daughter into the world in 2020.
Despite winning the Fans Player of the Season, he 'had to go' according to Zamparini, who sold him to Norwich and went on to make just the one Premier League appearance.
Dybala and Belotti's good behaviour off the pitch has seen them have far better careers.
The former has won five Serie A title with Juventus and starred for Argentina - something Lafferty predicted when he said he can 'take over' from international teammate Lionel Messi.
Belotti has also gone on to bigger and better things since leaving Palermo, netting 94 goals for Torino in Serie A after his move there in 2015 and winning Euro 2020 with Italy.
Both players have been linked with big-money moves away from Italy, with some of the biggest clubs in the world reportedly touting their services.
And if Dybala does end up making the move to Liverpool, let's hope he makes the short trip north of the border to see his old pal Lafferty, 34, and currently plying his trade at Kilmarnock.