Carlo Ancelotti's side suffered their first domestic defeat of the season to Rayo Vallecano on Monday night, with Oscar Trejo's 67th-minute penalty sealing a 3-2 win for the hosts.
As a result, Real missed the chance to rise back above Barcelona to the top of the table and occupy second place ahead of Thursday's game, and the gap to Xavi's side could increase the gap to five points if the Blaugrana beat Osasuna on Tuesday.
Here, Sports Mole rounds up Real Madrid's latest injury and suspension news ahead of their clash with Cadiz, who currently sit 19th in the standings.
Karim Benzema
Status: Minor doubt
Type of injury: Thigh
Possible return date: November 10 (vs. Cadiz)
Karim Benzema continues to struggle with muscular fatigue in his left thigh and was not able to contribute against Rayo Vallecano. It remains to be seen if the Ballon d'Or winner can return here, but reports have now claimed that he could be a doubt for France's opening World Cup match against Australia.
Antonio Rudiger
Status: Major doubt
Type of injury: Hip
Possible return date: November 10 (vs. Cadiz)
Antonio Rudiger was also absent from Monday's game due to a hip issue, which is not thought to be anything more than overload, but Ancelotti is not optimistic about the defender's chances of returning here.
REAL MADRID'S SUSPENSION LIST
Real Madrid have no players suspended for this match, and Toni Kroos will be back from a ban served on Monday night following his red card against Girona.