Both sides secured a return to winning ways last time out, and they now set out to pick up where they left off in their most recent outings.
Match preview
Wrexham showed great resolve to narrowly see off the threat of Aldershot in a thrilling 4-3 encounter at Recreation Ground on Saturday afternoon.
A first-half brace from Paul Mullin and Corey Jordan's own goal saw Phil Parkinson's men lead 3-2 at half time, after which Jordan Tunnicliffe inadvertently put the ball past his own goalkeeper to level matters, only for Sam Dalby to decide the game with a late winner.
Consequently, the Red Dragons have moved to within six points of Notts County at the top of the National League table despite playing two games fewer.
Coming up next is the challenge of an opposing outfit who have only come out on top in one of the previous nine meetings between the teams across all competitions.
Unbeaten in 20 matches on home turf leading up to Tuesday's contest, the hosts will fancy themselves to secure another impressive result in front of their fans.
Scunthorpe secured a first home win since January courtesy of a 3-2 victory over Dagenham & Redbridge at the Sands Venue Stadium on Saturday.
Jimmy Dean's men fell behind to Harry Phipps's opener after which goals from Ben Richards-Everton, Cameron Wilson and Liam Feeney turned the game on its head, rendering Dean Rance's late strike inconsequential.
With 26 points picked up from their 31 league outings so far, the Irons sit bottom but one in the league standings, four points adrift of safety.
Off the back of a first away win in 16 games in their last outing on the road, Tuesday's hosts go in search of back to back victories on the road for the first time since July.
Wrexham National League form:
W
W
W
W
D
W
Wrexham form (all competitions):
D
W
L
W
D
W
Scunthorpe United National League form:
W
L
W
D
L
W
Team News
Paul Mullin is now up to 24 league goals for Wrexham this season, making him one to keep an eye on as he continues his pursuit of Macaulay Langstaff at the top of the scoring charts.
Jake Bickerstaff remains unavailable through a long-term muscle problem, and the 21-year-old is ruled out of contention for the home side here.
Scunthorpe's Liam Feeney will be pushing for a place in the starting lineup after the Englishman came off the bench to good effect last time out.
Will Smith was fit enough to be named on the visitors' bench against Dag & Red, meaning that the defender could be in line for a return to action.
Wrexham possible starting lineup:
Howard; Cleworth, O'Connell, Tozer; Mendy, Young, Jones, Forde; Mullin, Palmer, Lee
Scunthorpe United possible starting lineup:
Chapman; Ogle, Boyce, Richards-Everton, Leake; Bunker, Butterfield, Beestin; Pugh, Wilson, Elliott