The hosts saw their three-game winning streak come to an end last time out, while their visitors made a much-needed return to winning ways.
Match preview
Trabzonspor were on the receiving end of a narrow 2-1 defeat against Hatayspor in the sides' encounter at the Yeni Hatay Stadyumu on Saturday afternoon.
Abdullah Avci's men opened the scoring early on through Enis Bardhi after which second-half goals from Ayoub El Kaabi and Bertug Yildirim turned the match on its head.
As a result, the Black Sea Storm have dropped to sixth place in the Turkish Super Lig table, five points adrift of the final European spot.
Their next task sees them lock horns with an opposing outfit with little to choose between the teams as the most recent seven meetings have yielded two wins apiece and three draws.
Having won each of their last five matches on home turf without conceding, Wednesday's hosts have proven themselves to be a real force to reckon with in front of their fans.
Antalyaspor ended a seven-match winless streak across all competitions by seeing off the threat of Umraniyespor at the Antalya Stadyumu on Saturday.
Nuri Sahin's men fell behind to Umut Nayir's opener but managed to forge ahead through goals from Sam Larsson and Guray Vural, after which Onur Ayik restored parity just shy of the hour mark, before Fredy had the last say with a late winner.
Picking up their first league win since November, The Scorpions have now moved up to 13th place in the standings, opening up a two-point gap over the bottom three.
Currently on a run of just one victory in their last seven outings on the road, Wednesday's visitors will be keen to turn their away fortunes around heading into the second half of the season.
Trabzonspor Turkish Super Lig form:
L
W
L
W
W
L
Antalyaspor Turkish Super Lig form:
L
L
D
D
L
W
Team News
Trabzonspor's duo of Serkan Asan and Dorukhan Tokoz are both unavailable for Wednesday's affair as they continue to nurse long-term knee injuries.
Edin Visca also misses out due to a collarbone injury, while Marek Hamsik is yet to fully recuperate from a calf problem which saw him fail to feature last time out.
Luiz Adriano remains suspended after the Brazilian received his marching orders in the final knockings of Antalyaspor's defeat to Galatasaray.
The away side are also set to be without the services of forwards Houssan Ghacha and Haji Wright, who are currently down with muscle injuries.
Trabzonspor possible starting lineup:
Cakir; Peres, Bartra, Vitor, Elmali; Siopis, Bardhi, Yazici; Djaniny, Bakasetas, Gomez
Antalyaspor possible starting lineup:
Leite; Vural, Toprak, Sari, Balci; Rakip, Fernando; Gumus, Nakajima, Sinik; Larsson