Back-to-back wins since Daniele De Rossi's arrival have helped the Giallorossi inch up the Serie A standings, while their visitors have recently slipped back into the drop zone.
Match preview
Making an immediate impact upon his installation as Roma boss following Jose Mourinho's sacking, Daniele De Rossi led his new side to successive Serie A victories at the end of January, to keep them in the hunt for Champions League qualification.
After seeing off Hellas Verona on his dugout debut, the ex-Giallorossi midfielder oversaw last week's 2-1 success at Salernitana, and Roma could now win three league games in a row for the first time since October.
Paulo Dybala struck from the spot before captain Lorenzo Pellegrini doubled their lead at Stadio Arechi, and the capital club held on for three points that lifted them to fifth in the table.
Appointed interim manager until the end of the season, De Rossi has already started to build some momentum, with his switch to a more offensive setup featuring a back four paying off against two of the top flight's lesser lights.
Roma remain unbeaten at home since September, so they will surely be confident of sealing victory over another Serie A struggler before two major tests in the days ahead: Inter Milan visit Rome next weekend, while Dutch champions Feyenoord then await in the Europa League.
Having both scored for 13 consecutive home matches in the league and lost none of their last eight games against Cagliari at the Olimpico - keeping a clean sheet on six occasions - precedent is certainly on the Giallorossi's side.
In fact, Cagliari have won only one of their last 17 Serie A matches against Monday's hosts, losing 12 times - including each of the last three.
Head coach Claudio Ranieri returns to his former club in need of points to stay afloat in the Italian elite, with his side mired in the relegation zone after losing at home to Torino last time out.
The Sardinian side payed tribute to club legend Gigi Riva before kickoff, but conceding two first-half goals put them on the back foot against in-form opponents and Nicolas Viola's 77th-minute strike only served to reduce their margin of defeat.
Several teams are embroiled in a busy Serie A survival race this year, so the vastly experienced Ranieri will not start panicking now, but his main priority must be to improve Cagliari's dismal away form.
Stretching back to the Rossoblu's relegation campaign of 2021-22, they have not won any of their last 16 top-flight fixtures on the road, losing no fewer than 11 and failing to even score in half.
Roma Serie A form:
W
L
D
L
W
W
Roma form (all competitions):
D
L
L
W
W
W
Cagliari Serie A form:
L
D
D
W
L
L
Cagliari form (all competitions):
D
L
D
W
L
L
Team News
Roma boss Daniele De Rossi will have two new signings at his disposal on Monday, and Galatasaray loanee Angelino could make his debut on the left flank due to Leonardo Spinazzola's likely absence.
Another acquisition, Tommaso Baldanzi, should start on the bench, to which Renato Sanches could return after missing more than a month with an ankle injury; Leandro Paredes is back from a one-match ban.
However, English duo Tammy Abraham and Chris Smalling are still unavailable, Evan Ndicka remains on international duty with AFCON hosts Ivory Coast, while Andrea Belotti and Marash Kumbulla have left the club on loan.
Skipper Lorenzo Pellegrini has scored in his last two appearances and could now find the net in three straight Serie A matches for the very first time. The Italy international is set to feature in a midfield trio, with Paulo Dybala and Stephan El Shaarawy supporting top scorer Romelu Lukaku up front.
Meanwhile, Claudio Ranieri added Yerry Mina and Gianluca Gaetano to his squad last week, and Mina is expected to slot straight into Cagliari's leaky defence.
Andrea Petagna could be retained in attack, as Gaetano Oristanio and Roma-owned Eldor Shomurodov are both injured, while Zito Luvumbo has just returned from the Africa Cup of Nations.
It remains to be seen whether Nicolas Viola will be promoted to the starting XI, with all three of his league goals this season coming from off the bench.
Roma possible starting lineup:
Patricio; Karsdorp, Mancini, Llorente, Angelino; Pellegrini, Paredes, Cristante; El Shaarawy, Dybala; Lukaku
Cagliari possible starting lineup:
Scuffet; Wieteska, Mina, Dossena; Zappa, Nandez, Makoumbou, Prati, Augello; Viola; Petagna