The teams are neck and neck in the Eredivisie table as it stands and this weekend's encounter has all the makings of an enthralling affair.
Match preview
Cambuur were left red-faced for the third game running following an agonising 1-0 defeat against Groningen at the Cambuur Stadion on Sunday.
Henk de Jong's men were in the ascendancy for the majority of the contest but conceded a 71st-minute opener to Tomas Suslov which proved to be the difference.
Consequently, The Yellow-Blues have dropped to 13th in the league table and are currently outside the relegation zone only on goal difference.
Awaiting them next is the challenge of an opposing outfit who are yet to come out on top in any of the last 12 meetings between the teams since 2013.
With one win in six outings on the road heading into this weekend's clash, Saturday's visitors will need to turn their away fortunes around as they look to breathe life into their domestic campaign.
Waalwijk suffered a first away defeat this term thanks to a narrow 1-0 loss against PSV Eindhoven at the Philips Stadion on Sunday afternoon.
Joseph Oosting's men put on a dogged performance and looked set to come away with a hard-fought point before Cody Gakpo netted a late penalty to decide the game.
Having recorded six points from as many games so far, RKC are currently 12th in the Eredivisie standings and could move into the top half with all three points in their next outing.
Off the back of a five-goal haul in their most recent home involvement, Saturday's hosts will be aiming to put on another attacking masterclass in front of their fans.
RKC Waalwijk Eredivisie form:
Cambuur Eredivisie form:
Team News
Twenty-five-year-old Robin Maulun is ruled out for Cambuur this weekend due to a thigh problem which has seen him miss four games on the bounce.
The away side are also set to be without the services of defender Maxim Gullit, who has not featured since picking up a knee injury in February.
Waalwijk's Florian Jozefzoon was absent from the defeat to PSV Eindhoven and the Suriname international is set to sit out Saturday's contest as well.
Julen Lobete is expected to retain his place in the starting XI after he was handed his first start of the season as a result of Jozefzoon's unavailability last time out.
RKC Waalwijk possible starting lineup:
Vaessen; Lutonda, Van den Buijs, Lelieveld, Adewoye, Gaari; Bakari, Anita, Clement; Lobete, Kramer
Cambuur possible starting lineup:
Virginia; Wermeskerken, Tol, Smand, Bangura; Van Kaam, Hoedemakers, Paulissen; Balk, Uldrikis, Van der Water