The away side, on the other hand, go in search of back to back victories for the first time this term having returned to winning ways last time out.
Match preview
PSV Eindhoven kicked off their Europa League campaign with a 1-1 stalemate against Norwegian champions Bodo/Glimt on Thursday evening.
Ruud van Nistelrooy's men were breached on the stroke of half time by Albert Gronbaek after which Cody Gakpo restored parity just past the hour mark.
Prior to that, the Rood-witten saw their 100% record in the Eredivisie come to an end courtesy of a 2-1 defeat against FC Twente at De Grolsch Veste.
Up next is the task of facing off against an opposing outfit who are on a run of five straight defeats in this fixture dating back to 2019.
Having already netted 12 times in three league games on home turf so far, Sunday's hosts will be looking to put on another attacking masterclass in front of their fans.
RKC Waalwijk got their season up and running at the fifth time of asking thanks to a comprehensive 5-2 victory over Excelsior at the Mandemakers Stadion on Sunday.
Shawn Adewoye and Pelle Clement were on target to cancel strikes from Julian Baas and Redouan el Yaakoubi before Thierry Lutonda, Vurnon Anita and Michiel Kramer all got on the scoresheet to complete a remarkable turnaround.
Consequently, Joseph Oosting's men have moved up to eighth place in the Eredivisie table and are just a point behind the last European place.
With just one victory from their last nine matches on the road across all competitions, Sunday's visitors have it all to do as they seek to end their woeful run away from home.
PSV Eindhoven Eredivisie form:
PSV Eindhoven form (all competitions):
RKC Waalwijk Eredivisie form:
RKC Waalwijk form (all competitions):
Team News
Luuk de Jong remains sidelined for PSV Eindhoven due to a calf injury, and the Netherlands international is not expected to play any part in this one.
Jamal Gonzaga and Noni Madueke are also unavailable due to ankle injuries, while Mauro Junior is yet to fully recover from a groin problem.
Yorbe Vertessen was handed his first start of the campaign in midweek, but the forward is expected to drop out of the starting XI for this one.
Twenty-one-year-old Julen Lobete came off the bench to good effect for Waalwijk last time out and could be rewarded with a place in the lineup here.
PSV Eindhoven possible starting lineup:
Benitez; Mwene, Teze, Obispo, Max; Veerman, Til, Sangare; Saibari, Gakpo, Simons
RKC Waalwijk possible starting lineup:
Vaessen; Lelieveld, Gaari, Adewoye, Van den Buijs, Lutonda; Bel Hassani, Anita, Clement; Kramer, Lobete