Despite currently being 22nd in the table the hosts head into the game on the back of a victory, which is the opposite of the visitors.
Match preview
Morecambe have had a difficult first half of the campaign having only won four matches throughout the season, which has left them in the relegation zone.
However, they started the new year in impressive fashion by earning three points against Burton Albion with a resounding 5-0 result.
Braces from both Kieran Phillips and Caleb Watts as well as a goal from Jensen Weir secured the win, with this marking consecutive victories for the team.
Not only did the Shrimps win both of their most recent matches, but they were able to keep clean sheets in each of them.
The performances have helped to build Morecambe's chances of survival as a win on Saturday has the potential of getting the club out of the relegation zone.
While the visitors cannot fall into the bottom four this weekend, they are hovering dangerously above the relegation spots themselves.
The Robins are currently 18th in the table and head into Saturday's fixture on the back of a 2-1 defeat against Bristol Rovers.
Alfie May's second-half goal proved to be nothing more than a consolation in the grand scheme of things, but the team will push to get back on track this weekend.
Cheltenham Town were able to defeat Morecambe earlier this season when the two teams first met, with Ben Williams scoring the only goal of the game.
However, away from home the Robins have not been as dominant, with a lack of goals proving to be a problem for them in those matches so far.
Morecambe League One form:
L
D
L
L
W
W
Morecambe form (all competitions):
L
D
L
L
W
W
Cheltenham Town League One form:
W
W
L
L
W
L
Cheltenham Town form (all competitions):
W
L
W
L
W
L
Team News
Derek Adams could hand Dynel Simeu his debut this weekend after he signed on loan from Southampton until the end of the season.
However, one player that Morecambe will no longer be able to call upon is Ousmane Fane, as the club mutually cancelled his contract earlier this week.
The hosts are not the only team who have recently lost a player as James Taylor has returned to Bristol City following a loan period.
Charles Raglan could be an option once again for the visitors following his suspension, boosting the squad depth for Cheltenham.
Morecambe possible starting lineup:
Ripley; Delaney, Bedeau, Rawson; Cooney, Weir, Shaw, Gibson, Watts; Stockton, Phillips
Cheltenham Town possible starting lineup:
Southwood; Taylor, Long, Freestone; Jackson, Sercombe, Bonds, Ferry; N'Lundulu, Broom, May
We say: Morecambe 2-0 Cheltenham Town
Morecambe head into this match in the relegation zone which is why most people will be presuming that the visitors are the favourites in this one.
Despite that, the Shrimps have been performing well in recent matches and that momentum should help them secure another victory.