Neither team managed to come out on top in their respective opening fixtures last time out, and they will be keen to get themselves up and running by securing all three points here.
Match preview
Luzern had to make do with a share of the spoils in their curtain-raiser against Winterthur which ended goalless at Stadion Schutzenwiese on Saturday.
Despite seeing more of the ball over the course of the contest, Mario Frick's men were unable to create enough clear-cut opportunities to break the deadlock.
However, Die Leuchten managed to rediscover their touch in front of goal five days later as they claimed a 2-1 win over Djurgarden in the first leg of the sides' Conference League qualifier.
Next up is a first-ever meeting against an opposing outfit who only just gained promotion to the Swiss Super League after seven years in the lower divisions.
Off the back of three consecutive home victories by a combined score of 8-2, Sunday's hosts will back themselves to get the job done in front of their fans once again.
Lausanne-Ouchy could not have asked for a worse start to life in the top flight as they fell to a 3-0 defeat against Lugano at Stade Olympique de la Pontaise on Wednesday.
Anthony Braizat's men fell behind to Renato Steffen's opener, after which second-half goals from Zan Celar and Mohamed Amoura put the result beyond doubt.
Albeit only on goal difference, SLO currently sit bottom of the standings after the first matchday heading into this weekend's involvement.
Having recently seen their four-game unbeaten streak on the road come to an end, Sunday's visitors now set out to avoid back to back defeats away from home for the first time in over a year.
Luzern Swiss Super League form:
Luzern form (all competitions):
Stade Lausanne-Ouchy Swiss Super League form:
L
Team News
Luzern's Jakub Kadak found the back of the net within minutes of coming on as a substitute in midweek, and he could be rewarded with a place in the starting XI.
Kemal Ademi will be aiming to pick up where he left off after opening his account for the home side at the second time of asking last time out.
New arrival Jeremy Vachoux was named on the Lausanne-Ouchy bench last time out, but the goalkeeper will be pushing to make a first appearance for his new employers.
Twenty-three-year-old Florian Danho has netted in two of his last three outings for the away side, making the Frenchman one to keep an eye on.
Luzern possible starting lineup:
Loretz; Frydek, Burch, Beka, Ottiger; Beloko, Dorn, Meyer; Okou, Ademi, Spadanuda
Stade Lausanne-Ouchy possible starting lineup:
Da Silva; Gassama, Hajrulahu, Pos, Heule; Akichi, Hamdiu; Mulaj, Qarri, Ajdini; Danho