While Inter are red-hot Scudetto favourites following their superb start to 2024, the hosts have lost five of their last six matches and are slipping closer to the trapdoor.
Match preview
After Tuesday's 1-0 win over Atletico Madrid, in the first leg of their Champions League last-16 tie, Inter are one small step closer to reaching the final of Europe's top competition for the second time in as many seasons.
Thanks to a late Marko Arnautovic strike at San Siro, the Nerazzurri not only have a precious lead to take into next month's return in Madrid, but they have also lost just one of their last 14 Champions League matches - to Manchester City in the 2023 decider - while keeping nine clean sheets in the process.
Following slip-ups from title rivals Juventus and AC Milan last week, Simone Inzaghi's side are also well clear at the Serie A summit, and with 63 points on the board already, only in 2007 have the second-city giants posted more points at this stage of a campaign.
After victory over Juve in the Derby d'Italia, Inter's most recent victims have been Roma and rock-bottom Salernitana, both of whom were hit for four goals: last weekend, Arnautovic joined captain and top scorer Lautaro Martinez on the scoresheet in a 4-0 defeat of the latter.
Despite losing to Bologna in the Coppa Italia, the Nerazzurri have already swept to a third straight Supercoppa Italiana since the turn of the year and appear to be on course for more silverware.
Inzaghi's men will now aim to maintain their nine-point lead when journeying south in pursuit of another club record: having scored in 19 consecutive away Serie A matches, they could now reach 20 for the first time in Inter's long history.
Not only are their visitors in frankly frightening form coming into Sunday's game, but precedent does not favour Lecce either: the Salentini have tasted just one success in their last 15 league meetings with Inter, losing 11.
In fact, they have failed to even score in eight - including the last two, which both ended 2-0 in favour of the Nerazzurri - so there is little expectation that an upset can be produced at Via del Mare.
After playing out the final fixture of their February schedule, Lecce will face a potentially decisive trio of matches - versus Frosinone, Hellas Verona and Salernitana - that could prove the difference between avoiding relegation or heading back to Serie B.
First, though, Roberto D'Aversa must steel his troops for an assault by the league leaders, following a truly dismal run of results.
Over the last nine Serie A matchdays, no other team have lost more matches than Lecce (seven) or accrued fewer points (four), and they have inevitably slid towards the drop zone. Though the Puglian club can rarely be written off on home turf, that makes toppling mighty Inter all the more unlikely.
Lecce Serie A form:
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Inter Milan Serie A form:
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Inter Milan form (all competitions):
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Team News
With one eye on next Wednesday's clash with Lombardy rivals Atalanta BC - one of Italy's in-form sides - Inter boss Simone Inzaghi may make some changes to the XI that started against Atleti last time out.
Fringe players such as Marko Arnautovic, Davide Frattesi and back-up goalkeeper Emil Audero may feature for the visitors, while wing-backs Denzel Dumfries and Carlos Augusto could come in on the right and left flank respectively.
If not rested, Lautaro Martinez will lead the line: 'El Toro' is one goal away from both notching his 100th in Serie A and matching his best tally in a league season (21). However, strike partner Marcus Thuram will not be present, having sustained an adductor injury on Tuesday, joining Francesco Acerbi (calf) and Juan Cuadrado (Achilles) on the sidelines.
Meanwhile, Lecce will be missing two defenders this weekend, as Patrick Dorgu and Marin Pongracic must both serve suspensions - the former for yellow-card accumulation, the latter for being sent off against Torino.
Battling it out with Nikola Krstovic to start up front, Roberto Piccoli - who scored his first Serie A goal versus Inter, back in December 2020 - has four to his name so far this season; three have come in home games, including the recent 3-2 thriller against Fiorentina.
Lecce possible starting lineup:
Falcone; Gendrey, Touba, Baschirotto, Gallo; Kaba, Ramadani, Oudin; Almqvist, Krstovic, Banda
Inter Milan possible starting lineup:
Audero; Bisseck, De Vrij, Bastoni; Dumfries, Frattesi, Calhanoglu, Mkhitaryan, Augusto; Martinez, Arnautovic