Meanwhile, the away side make the journey to the Turkish capital aiming this weekend to pick up a third straight win across all competitions.
Match preview
Istanbul Basaksehir fell to a 1-0 defeat against Antalyaspor when the sides went head to head at the Corendon Airlines Park on Sunday evening.
Cagdas Atan's men fell behind to Dario Saric's opener 15 minutes into the contest and that turned out to be the all-important moment in the clash.
As a result, The Grey Owls remain 17th in the Turkish Super Lig table after 10 rounds of matches, albeit just only one point adrift of safety.
Awaiting them next is the challenge of an opposing outfit who have only come out on top in one of the last 14 editions of this fixture dating back to 2011.
However, that solitary triumph did come in the most recent encounter back in May when Sunday's hosts fell to a 2-1 defeat in the Turkish Cup.
Ankaragucu eased past the threat of Arguvan to book their place in the next round of the Turkish Cup thanks to a 2-0 win at the Eryaman Stadium on Wednesday.
Emre Belozoglu's men took the lead midway through the second half through Olimpiu Morutan before Federico Macheda made sure of the result 13 minutes from time.
This came off the back of a 2-0 victory over Samsunspor for MKE which has seen them move up to 11th in the standings, one point behind the top half.
Having won just one of five matches on the road leading up to Sunday's affair, the visitors will be keen to get themselves going away from home.
Istanbul Basaksehir Turkish Super Lig form:
L
L
D
W
D
L
Ankaragucu Turkish Super Lig form:
W
D
L
W
L
W
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Team News
Basaksehir's Muhammed Sengezer has missed the last seven matches through a muscle problem and is unavailable for this weekend's game as well.
The home side will also be without the services of Efe Koyuncu through a knock, while Patryk Szysz misses out due to a long-term knee problem.
Thirty-year-old Stelios Kitsiou remains out of contention for Ankaragucu with a knee problem which he picked up in the final week of September.
Ali Sowe was on target in the last meeting between this weekend's opponents and the Gambia international will be looking to deliver the goods once again
Istanbul Basaksehir possible starting lineup:
Babacan; Lima, Opoku, Ba, Duarte; Aleksic, Tekdemir, Pelkas; Dennis, Turuc, Brandao
Ankaragucu possible starting lineup:
Gungordu; Hanousek, Mujakic, Radakovic, Bilazer; Bekiroglu, Cigerci; Rodrigues, Pedrinho, Chatzigiovanis; Sowe