Meanwhile, the away side make the trip to Milan aiming to avoid a fourth consecutive loss and get their 2022/23 Serie A campaign up and running.
Match preview
Inter Milan were sent crashing down to earth in Friday's meeting versus Lazio at the Stadio Olimpico which ended in a comprehensive 3-1 defeat.
After going behind to Felipe Anderson's opener, Simone Inzaghi's men hit back through Lautaro Martinez before goals from Luis Alberto and Pedro decided the contest.
As a result, I Nerazzurri have slipped to seventh place in the league standings but are only just a point adrift of all six teams above them.
Next up for the 19-time Italian champions is the challenge of an opposing outfit with just one victory in the previous 11 meetings between the sides.
Off the back of five consecutive Serie A wins on their own patch, Tuesday's hosts will fancy themselves to secure all three points in front of their fans once again.
Cremonese came away empty-handed from the third game running following a 2-1 defeat against Torino at the Stadio Giovanni Zini on Saturday.
Massimiliano Alvini's men went two goals down to strikes from Nikola Vlasic and Nemanja Radonjic before Leonardo Sernicola pulled one back with 10 minutes left.
One of two teams yet to record a single point this term, I Grigiorossi are currently bottom but one in the league table, ahead of Monza only on goal difference.
Having lost all but one of their last six outings on the road, Tuesday's visitors will be desperate to get themselves back on track away from home and kickstart their Serie A campaign.
Inter Milan Serie A form:
Inter Milan form (all competitions):
Cremonese Serie A form:
Cremonese form (all competitions):
Team News
The duo of Dalbert and Gabriel Brazao are long-term absentees for Inter Milan and neither of them is expected to feature in Tuesday's contest.
Meanwhile, Romelu Lukaku is also set to sit out this one with a thigh injury and the striker could possibly be absent from this weekend's Milan derby.
Following a five-game scoreless streak, Lautaro Martinez has now found the back of the net in consecutive matches and is definitely one to keep an eye on.
Leonardo Sernicola came off the bench to good effect for Cremonese last time out and the Italian could be rewarded with a place in the lineup here.
Twenty-two-year-old Gonzalo Escalante will be keen to retain his starting spot having recently made his return to action from a suspension
Inter Milan possible starting lineup:
Handanovic; Bastoni, De Vrij, Skriniar; Dimarco, Gagliardini, Brozovic, Barella, Dumfries; Martinez, Dzeko
Cremonese possible starting lineup:
Radu; Aiwu, Bianchetti, Vasquez; Baez, Pickel, Escalante, Valeri; Dessers, Zanimacchia, Okereke