Having suffered a 1-0 loss in last week's reverse leg, the Venezuelan side will head into the game seeking to overturn their one-goal deficit and secure a place in the last-four.
Match preview
Independiente del Valle continued their fine start to the new Ecuadorian LigaPro campaign as they saw off Orense when the sides squared off last Saturday.
In a thrilling contest at the Estadio 9 de Mayo, Jose Andrade restored parity on the hour mark after to cancel out Joao Ortiz's first-half opener but Jonathan Bauman converted his 79th-minute penalty to put the visitors ahead once again.
Martin Anselmi's men have now picked up three wins and one draw from their opening five games in the LigaPro to sit third in the league standings, level on 10 points with second-placed Emelec and one off Aucas at the top of the pile.
They now turn their attention to the Copa Sudamericana, where they have enjoyed a fine campaign so far, seeing off Lanus in the round of 16 before claiming a 1-0 first-leg win over Deportivo Tachira in the quarter-finals last time out.
Elsewhere, Deportivo Tachira failed to arrest their slump in the Venezuelan top flight as they fell to a 2-0 loss at the hands of league leaders Zamora FC last time out.
After an uneventful first half at the Estadio Agustin Tovar, Danny Perez and Erickson Gallardo netted in a two-minute spell to hand Noel Sanvicente's side all three points.
Deportivo Tachira, who are currently fourth in the Primera Division, have now failed to win any of their last four games across all competitions, picking up two draws and losing twice since a 3-0 victory over Metropolitanos on July 16.
While Juan Tolisano's side head into Tuesday looking to arrest this slump and overturn their deficit, they face a spirited opposing side who are unbeaten in four straight games and have lost just once on home turf since May.
Deportivo Tachira are also winless in all but one of their last seven away games across all competitions — losing four and claiming two draws — with their penalty shoot-out win over Santos in the second leg of their Copa Sudamericana last-16 clash being the only exception.
Independiente del Valle Copa Sudamericana form:
Independiente del Valle form (all competitions):
Deportivo Tachira Copa Sudamericana form:
Deportivo Tachira form (all competitions):
Team News
Independiente de Valle will take to the pitch without Nicolas Previtali, who has been out of action since April after suffering a cruciate ligament injury.
Anselmi will also be unable to call upon the services of veteran midfielder Jaime Ayovi after the 34-year-old received his marching orders in the first leg.
Bauman took his goal tally to 11 in the Ecuadorian top flight with his strike against Orense last time out and the 31-year-old will look to come up trumps for Los Negriazules once again.
Meanwhile, Deportivo Tachira head into Tuesday with a clean bill of health and no suspension concerns, giving Tolisano the luxury of a full strength squad.
Anthony Uribe started off the bench against Zomora last time out, but the 31-year-old should be recalled to the starting XI, teaming up with Yerson Chacon and Robert Hernandez in the final third.
Independiente del Valle possible starting lineup:
Ramirez; Carabajal; Schunke, Segovia; Fernandez, Faravelli, Sornoza, Minda; Angulo, Bauman, Ortiz
Deportivo Tachira possible starting lineup:
Varela; Azmahar, Camacho, Gutierrez, Marrufo; Totolero, Flores, Cova; Chacon, Hernandez, Uribe
We say: Independiente del Valle 3-1 Deportivo Tachira
Independiente will look to pick up where they dropped off against an opposing side who have managed just one win in seven away games across all competitions. We are backing Anselmi's men to make use of their home advantage and claim a second-leg victory.