The hosts set out to secure back to back victories having ended an eight-game winless run last time out, while the away side will be looking to return to winning ways.
Match preview
Heerenveen showed great resolve to just about emerge triumphant from a five-goal thriller against Ajax in Sunday's meetings between the teams.
Despite racing to a three-goal lead thanks to two goals from Pelle van Amersfoort either side of Osame Sahraoui's effort, Kees van Wonderen's men had to hold on for the final 10 minutes after conceding Pawel Bochniewicz's own goal and a Chuba Akpom strike.
As a result, De Superfriezen have moved up to 11th place in the Eredivisie table and now have PEC Zwolle in their sights in the race for Europe.
Next on the menu is the challenge of an opposing outfit who have won just two of the last 17 editions of this fixture across all competitions.
Off the back of a first home victory of 2024 last time out, Saturday's hosts now go in search of consecutive wins in front of their fans for the first time since December.
Go Ahead Eagles had to make do with a share of the spoils from their meeting, against Zwolle which ended in a 1-1 draw at De Adelaarshorst on Sunday.
Rene Hake's men looked set to come away empty-handed after going behind to Lennart Thy's 77th-minute opener, only for Mats Deijl to restore parity from the penalty spot in second-half stoppage time.
With 31 points picked up from 21 games so far, the pride of the IJssel Kowet sit sixth in the standings, one point behind AZ Alkmaar in fourth.
Having secured wins in each of their last two away matches, Saturday's visitors will be confident of getting the job done on enemy territory once again.
Heerenveen Eredivisie form:
L
D
L
D
D
W
Heerenveen form (all competitions):
L
D
L
D
D
W
Go Ahead Eagles Eredivisie form:
D
L
W
D
W
D
Go Ahead Eagles form (all competitions):
L
L
W
D
W
D
Team News
Mats Kohlert was shown a fifth yellow card of the season last time out, meaning that the Heerenveen man is ineligible to play any part here.
Ion Nicolaescu is also out of contention for the home side through a muscle problem, but the Romanian is making steady progress with respect to his recovery.
Go Ahead Eagles midfielder Philippe Rommens remains sidelined with an ankle problem which has seen him miss each of the last four matches.
Twenty-year-old Pim Saathof missed his side's last outing with a knock, and his involvement in this weekend's contest currently hangs in the balance.
Heerenveen possible starting lineup:
Van der Hart; Braude, Van Beek, Bochniewicz, Kohlert; Olsson, Haye; Walemark, Brouwers, Sahraoui; Van Amersfoort
Go Ahead Eagles possible starting lineup:
De Lange; Deijl, Amofa, Kramer, Kuipers; Linthorst, Blomme; Adekanye, Edvardsen, Breum; Edvardsen