On the other hand, the away side make the trip to the Abe Lenstra Stadion aiming to avoid a sixth defeat in a row across all competitions.
Match preview
Heerenveen fell to a 2-0 defeat against league leaders PSV Eindhoven when the two teams went head to head at the Philips Stadion on Thursday.
Kees van Wonderen's men went into the interval trailing to Guus Til's opener after which Ricardo Pepi sealed the deal 12 minutes from time.
As a result, De Superfriezen remain eighth in the Eredivisie table, level on points with Fortuna Sittard in the race for the final European spot.
Awaiting them next is the challenge of an opposing outfit who have been beaten in all but one of the last 12 editions of this fixture dating back to 2003.
Currently on a run of four straight home wins, Saturday's hosts will be confident of getting the job done in front of their fans once again.
FC Volendam saw their downward spiral hit a new low as they suffered a 3-1 defeat to defending champions Feyenoord in Thursday's encounter at De Kuip.
Matthias Kohler's men fell behind to Quinten Timber's early strike but managed to restore parity through Lequincio Zeefuik before late second-half goals from Santiago Gimenez and Igor Paixao decided the game.
With eight points picked up from 15 league matches so far, Het Andere Oranje sit bottom of the standings and are five points adrift of safety.
Having lost eight of their last nine away involvements, Saturday's visitors have it all to do as they look to avoid another fruitless outing on the road.
Heerenveen Eredivisie form:
W
L
W
W
W
L
FC Volendam Eredivisie form:
L
D
L
L
L
L
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Team News
Pawel Bochniewicz has missed each of Heerenveen's last three matches with a back problem and will not feature in this weekend's contest as well.
Jan Bekkema is also out of contention for the home side through injury although the goalkeeper is closing in on a return to action.
Dutch duo Joey Antonioli and Koen Blommestijn are both unavailable for Volendam as Luke Le Roux also misses out.
Twenty-six-year-old Benaissa Benamar is an injury doubt for the visitors after he was forced off in the first half of the defeat to Feyenoord last time out.
Heerenveen possible starting lineup:
Noppert; Kohlert, Van Ottele, Van Beek, Braude; Brouwers, Haye, Olsson; Sahraoui, Van Amersfoort, Nunnely
FC Volendam possible starting lineup:
Backhaus; Plat, Flint, Mbuyamba, Buur; Mirani, Twigt, Booth; Ould-Chikh, Zeefuik, De Haan