On the other hand, the away side will be looking to pick up back to back victories for the first time since March having returned to winning ways last time out.
Match preview
Trabzonspor saw off the threat of Fatih Karagumruk in superb style courtesy of a 4-1 victory when the teams faced off at the Akyazi Stadyumu on Monday.
Nenad Bjelica's men took the lead in the fifth minute through Marc Bartra but conceded a 14th-minute equaliser to Mbaye Diagne before Batuhan Sen's own goal and a Trezeguet double got the job done.
As a result, the Karadeniz Firtinasi have moved up to sixth place in the Turkish Super Lig table but still sit a whopping 12 points behind the top four.
On the horizon next is the task of facing off against an opposing outfit who are yet to come out on top in any of the previous three editions of this fixture, losing two of them.
Off the back of five consecutive defeats on the road by a combined score of 14-4, Tuesday's visitors set out to turn their away fortunes around.
Giresunspor were awarded a 3-0 victory on Sunday with Gaziantep unable to participate in the sides' scheduled clash at the Gaziantep Stadyumu.
That was the second straight game in which Irfan Buz's men came away with three points and three goals having also benefited from Hatayspor's tragic and abrupt end to the season.
Having now picked up seven of the last nine points available, the Cotanaklar sit 16th in the standings, one point adrift of safety heading into the final three matchdays.
Currently on a run of one just defeat in their most recent six home involvements leading up to Tuesday's clash, the hosts will be confident of coming away with a positive result in front of their fans.
Giresunspor Turkish Super Lig form:
L
W
L
L
L
D
Trabzonspor Turkish Super Lig form:
D
L
L
W
L
W
Team News
Alexis Perez has missed Giresunspor's last four matches due to an elbow problem, while Vukan Savicevic remains unavailable due to a muscle problem.
The home side will also have to make do with the absence of Faustin Senghor, who is yet to recuperate from a thigh injury he picked up two months ago.
Thirty-year-old Stefano Denswil is out of contention for Trabzonspor due to a calf problem, which will keep him out for the remainder of the campaign.
Dorukhan Tokoz and Abdulkadir Parmak are both down with long-term knee injuries, and neither will play any part for the visitors in this one.
Following his brace last time out, Trezeguet is now up to 10 league goals this term - the most he has managed in a season since his first spell in Turkish football with Kasimpasa four years ago.
Giresunspor possible starting lineup:
Kaplan; Uludag, Seven, Arias, Bilazer; Campuzano, Saglam, Mejia; Serginho, Sainz, Bajic
Trabzonspor possible starting lineup:
Cakir; Larsen, Turkmen, Bartra, Bosluk; Siopis, Bakasetas; Visca, Omur, Trezeguet; Gomez