The hosts, meanwhile, will be hoping to build on a solid 0-0 draw away to Union Berlin from their last league match.
Match preview
Indeed, having conceded five goals without reply across two consecutive defeats to Stuttgart and Wolfsburg, Koln boss Steffen Baumgart would have been content to see his side leave the capital with a point last weekend.
With 17 points separating the two sides in the Bundesliga table, and Union Berlin unbeaten at home in the league for over a year, avoiding defeat was probably the best result The Billy Goats could realistically hope to achieve.
Baumgart's main concern may be regarding his side's lack of potency in attack in recent weeks, having blanked in five of their last six matches heading into Friday's encounter against Bochum at RheinEnergieStadion.
As such, it could be the perfect time to be playing the division's bottom-ranked outfit, who have lost their last four matches prior to their trip to Cologne.
Indeed, despite putting together a solid run of form in Thomas Letsch's first few months at the club to move outside of the relegation zone, Bochum have lost seven of their last eight matches in all competitions to fall back to the bottom of the table.
The bulk of Bochum's growing foundations under Letsch was built on strong home form, with the 54-year-old sensationally winning each of his first five league games at Vonovia-Ruhrstadion after being appointed in late September.
However, even that has deserted them in recent weeks, with a disastrous 2-0 defeat at home to relegation rivals Schalke 04 last weekend seeing their opponents swap places with them in the table.
With tough fixtures against Champions League representatives RB Leipzig and Eintracht Frankfurt either side of the international break, Letsch and his players are clearly under significant pressure to achieve a positive result on Friday.
FC Koln Bundesliga form:
D
D
W
L
L
D
VfL Bochum Bundesliga form:
L
W
L
L
L
L
VfL Bochum form (all competitions):
W
L
L
L
L
L
Team News
Koln's lack of goal threat has not been helped by long-term injuries to crucial attackers such as Sebastian Andersson, Mark Uth, Florian Dietz and Jan Thielmann, while defenders Luca Kilian, Mads Pedersen and Rijad Smaljic are all unavailable too.
After producing a disciplined performance against high-flying Union Berlin last time out, Baumgart is unlikely to make any changes to his starting XI, even if he will be hoping for more attacking fluency against weaker opponents.
Bochum, meanwhile, will travel without Simon Zoller, Gerrit Holtmann and Cristian Gamboa due to existing injury problems, but Philipp Hofmann shook off a cold to start against Schalke and should be included in the matchday squad once again.
Letsch may look to bring Cameroon international Pierre Kunde into his midfield after losing control in that area of the pitch during their damaging defeat to Schalke last weekend.
FC Koln possible starting lineup:
Schwabe; Schmitz, Hubers, Chabot, Hector; Martel, Skhiri; Maina, Ljubicic, Kainz; Tigges
VfL Bochum possible starting lineup:
Riemann; Janko, Masovic, Schlotterbeck, Soares; Forster, Kunde, Stoger; Asano, Hofmann, Antwi-Adjei
We say: FC Koln 2-0 VfL Bochum
Koln have lacked potency in attack in recent weeks, but their defensive record has been excellent on the whole, which should help them return to winning ways on Friday.
Bochum's away form has remained wretched all season long - winning just once on the road in the league - and they are likely to remain bottom by suffering another defeat.