A 1-0 defeat in gameweek one saw the Bruges outfit slip to a loss against the defending champions Royal Antwerp, while Charleroi secured a 1-1 home draw when they hosted Oud-Heverlee Leuven.
Match preview
It was going to take a storming performance by Cercle Brugge to stop Antwerp in their first Pro League game since claiming the title on a dramatic final day last term, and so it proved.
The goal that won the game was scored by Jesper Daland at the wrong end just before the interlude, but Miron Muslic's men could not respond despite a brief spell of pressure at the start of the second half.
A positive in defeat was the 1-0 score, undoubtedly an upgrade in performance after letting in seven in a 7-2 thrashing by Lille in their final pre-season friendly.
However, their lack of a cutting edge in front of goal was recognised before the season's commencement, with three of the club's four games ending without Cercle Brugge scoring.
Thus, Saturday's game represents a chance to find the back of the net and possibly win — something that has been a rarity for the club from Bruges.
As for Charleroi, who ended outside the continental playoff spots last season, they secured a creditable opening-day draw at home to Oud-Heverlee Leuven.
The circumstances of the point hurt from one perspective — Nathaniel Opoku's leveller came in the 84th minute — but a closer assessment shows OHL deserved the draw.
The Zebras played over 70 minutes short-handed in gameweek one, following Nikola Stulic's sending-off for violent conduct in minute 17, shortly after Oday Dabbagh put the home side ahead.
In the end, Felice Mazzu's team had to make do with a point, but they hope to avoid a repeat of playing an extended time disadvantaged on Saturday as they were in gameweek one.
Charleroi will be wary before this weekend's encounter due to a 4-1 beatdown in the corresponding fixture last season.
Cercle Brugge Belgian Pro League form:
L
Charleroi Belgian Pro League form:
D
Team News
Edgaras Utkus had to go off nine minutes after replacing Boris Popovic, and the injury sustained in Cercle's opening-day clash — now confirmed as a thigh muscle rupture — would keep him out of action for a while.
Despite his own goal, Daland is expected to start as one of the three centre-backs in the home side's 3-4-1-2.
Stulic is suspended for Charleroi after getting sent off early in gameweek one's clash with Oud-Heverlee Leuven.
The away side are sweating over the fitness of Marco Ilaimaharitra, who went off late on against OHL, but that does not depict the Zebras' injury bugbear — Nadhir Benbouali is out with a cruciate ligament rupture, Ken Nkuba is not expected back until September, while Jackson Tchatchoua (neck), Youssouph Badji (ankle), Jules Van Cleemput (tendonitis) and Damien Marcq (back) are all out.
Cercle Brugge possible starting lineup:
Warleson; Ravych, Popovic, Daland; Siquet, Francis, Van Der Bruggen, Deman; Gboho; Denkey, Somers
Charleroi possible starting lineup:
Koffi; Boukamir, Andreou, Knezevic; Rogelj, Morioka, Zorgane, Heymans, Mbenza; Bernier, Dabbagh