Both teams were beaten in their respective last outings and will be looking to get themselves back on track by securing all three points here.
Match preview
Burton Albion failed to pick up a third straight win as they fell to a 2-0 defeat against Northampton Town when the sides went head to head on Saturday.
Martin Paterson's men made a poor start to the contest and went into the break trailing by two thanks to strikes from Marc Leonard and Mitchell Pinnock.
As a result, The Yellow and Black Army have dropped down to 18th place in the League One table, five points clear of relegation danger having played one game more.
Awaiting them next is the challenge of an opposing outfit who are unbeaten in four of the previous five editions of this fixture across all competitions.
Off the back of consecutive defeats on home turf by a combined score of 3-0, Tuesday's hosts will be keen to turn things around in front of their fans.
Carlisle United were beaten for the eighth straight game following a 2-1 defeat against Bristol Rovers at the Memorial Stadium on Saturday.
Paul Simpson's men opened the scoring through Josh Vela before goals in either half from Chris Martin and Scott Sinclair turned the match on its head.
With 20 points amassed from 33 league outings so far, The Cumbrians remain rooted to the bottom of the standongs, a whopping 14 points adrift of safety.
Currently on an 11-game winless run on the road, Tuesday's visitors have it all to do as they go in search of their first away triumph since October.
Burton Albion League One form:
W
D
L
W
W
L
Carlisle United League One form:
L
L
L
L
L
L
Team News
Adedeji Oshilaja made his return to action for Burton against Northampton last time out and the defender is expected to retain his place for this one.
Twenty-one-year-old Kgaogelo Chauke remains a major doubt for the home side here having missed each of the last four matches through injury.
Jordan Gibson will be aiming to come up with the goods once again after finding the back of the net for Carlisle in the reverse fixture.
Josh Vela has made a decent start to life for the visitors since his loan move from Fleetwood and the Englishman is one to keep a close eye on.
Burton Albion possible starting lineup:
Crocombe; Hamer, Nsiala, Brayford, Sweeney, Bola; Oshilaja, Powell, Helm; Bennett, Ola-Adebomi
Carlisle United possible starting lineup:
Lewis; Armer, Mellish, Lavelle, Back; Charters, Neal, Vela; Gibson, Armstrong, Diamond