The Black Eagles dismissed Valerien Ismael earlier this week with the team in fifth place on 19 points, and quickly replaced him with the man that guided them to two league titles in his first stint in charge.
Match preview
Besiktas have struggled lately, with just one win in their last six games after starting the season with four victories in five matches.
The straw that broke the camel's back for former Barnsley and West Bromwich Albion man Ismael was the 2-1 defeat at Hatayspor on Monday, as Ze Luis and Kaan Kanak scored for the hosts to cancel out Wout Weghorst's first-minute strike for Besiktas.
In attack, the Black Eagles have scored 20 goals, a figure only bettered by the top two in the division, but they have also conceded the most goals among teams in the top half of the table.
A win in Gunes's first game back at the helm could see them climb back into the European places, depending on other results, and could start a revival of their title charge after last season's dismal sixth-place finish.
Weghorst, Jackson Muleka and Georges-Kevin N'koudou all have four goals in the league this season and will be hoping they can add to their tallies again this weekend.
Lowly Umraniyespor sit rock bottom of the league as the only team yet to win a game this season with just three draws to their name.
Last time, they lost their seventh game of the season against Fatih Karagumruk as Umut Nayir's third-minute goal was not enough with Davide Biraschi, Mbaye Diagne and Fabio Borini scoring for Andrea Pirlo's side.
They have not been completely played off the park in any of the defeats they have had this season, though, with that defeat last time out the first time they have lost by more than one goal this campaign.
Recep Ucar's side has picked up two of their three points on their travels, including an entertaining 3-3 draw with current league leaders Fenerbahce on the opening weekend.
In their first-ever season in the top flight of Turkish football, Umraniyespor have struggled to adapt but a win against one of the biggest teams in the country would be a perfect way to kickstart their campaign.
Besiktas Turkish Super Lig form:
L
D
D
W
D
L
Umraniyespor Turkish Super Lig form:
L
D
L
L
D
L
Team News
Gunes could make a host of changes in his first game in charge, but he will most likely be without Rachid Ghezzal after the winger missed the defeat to Hatayspor on Monday through injury, and Romain Saiss, who is recovering from a hamstring injury.
Weghorst is a slight doubt after carrying a knock into that game, so Cenk Tosun could be in line for a start, as could Gedson Fernandes after both were substitutes last time out.
Umraniyespor could welcome back Isaac Sackey after the Ghanian missed the last game through suspension, but will still be without defender Tomislav Glumac after his late red card against Kayserispor.
With the return of Sackey, Ucar could look to revert to a midfield five and a lone striker meaning Nayir will lead the line.
Besiktas possible starting lineup:
Destanoglu; Rosier, Sanuc, Montero, Masuaku; Ucan, Souza; N'Koudou, Fernandes, Muleka, Weghorst
Umraniyespor possible starting lineup:
Ozdemir; Goksu, Allyson, Eser, Lenjani; Geraldo, Sackey, Yilmaz, Avounou, Ayik; Nayir