The visitors are currently just outside of the relegation zone, placing pressure on each to pick up points for different reasons.
Match preview
With Benfica just one point behind Sporting Lisbon in the league table at the moment, there is an opportunity for them to move into the top spot with a victory at the weekend.
While the Eagles will be relying on their title challengers slipping up, they need to keep the pressure on as the season heads into its final section, especially since Sporting Lisbon has a game in hand.
Benfica head into Sunday on the back of a draw against Rangers in midweek where they relied upon an own goal from Connor Goldson to stop them from losing in the Europa League.
The draw extended Benfica's run without a victory to three games after defeats against Sporting Lisbon and Porto recently, which is a spell that Roger Schmidt will want to see come to an end.
The Eagles will also be keen to avenge the defeat they suffered against Estoril the last time they met, when the Canaries won a penalty shootout in the Taca da Liga semi-final.
That is something that the visitors will be looking to take confidence from considering they have only won six games throughout their league campaign to this point.
Estoril are currently only outside of the relegation zone due to goal difference, and that is placing plenty of pressure on them to start picking up points.
The Canaries have struggled on the road this season, winning just a single game, and they also head into this fixture on the back of four matches without a victory.
However, Vasco Seabra will remain confident he can guide the team to safety due to how close things are in the league table right now as a win could see them climb up to 12th depending on other results.
Estoril could easily find themselves in a much stronger position by the end of the weekend, but a stronger performance than the one that was defeated 3-1 by Vitoria SC will be required.
Benfica Primeira Liga form:
W
W
D
W
W
L
Benfica form (all competitions):
W
D
W
L
L
D
Estoril Praia Primeira Liga form:
D
W
L
L
D
L
Team News
The experience of Angel Di Maria will likely be relied upon this weekend as the Argentine forward has consistently provided quality for Benfica this season with eight goals and six assists to his name already.
However, the hosts will be without Juan Bernat again as his muscle injury that has kept him out since October is continuing to plague him, while there are also question marks over Alexander Bah who was unable to complete 90 minutes in midweek.
The visitors also have a plethora of injuries to consider at the moment, with Jordan Holsgrove currently out of action because of a muscle injury he suffered at the end of January.
Erick Cabaco is also on the treatment table, and will be throughout the rest of the reason due to an Achilles tendon injury, while former Benfica defender Pedro Alvaro has also been on the sidelines lately.
Benfica possible starting lineup:
Trubin; Aursnes, A. Silva, Otamendi, Morato; Neves, Luis; Di Maria, R. Silva; Mario; Cabral
Estoril Praia possible starting lineup:
Figueira; Basso, Volnei, Mangala; Tavares, Fernandes, Zanocelo, Araujo; Guitane, A Marques, J Marques
We say: Benfica 2-0 Estoril Praia
Both of their previous meetings this season have been closely contested, but considering Benfica are in the hunt to win the league at the business end of the season they will be looking to be a little more ruthless.
The gulf in class between the two teams should ultimately lead to the Eagles taking all three points here, particularly considering Estoril's poor away form.