Arsenal
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Out: None
Doubtful: Emile Smith Rowe (hip)
Aston Villa
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Out: Matty Cash (hamstring), Kortney Hause (ankle), Wesley (knee)
Doubtful: Emiliano Martinez (groin), Jack Grealish (shin)
Brighton & Hove Albion
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Out: Florin Andone (knee), Solly March (knee), Adam Webster (ankle)
Doubtful: Tariq Lamptey (thigh)
Burnley
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Out: Johann Berg Gudmundsson (hamstring), Ashley Barnes (thigh)
Doubtful: Erik Pieters (groin), Robbie Brady (ankle)
Chelsea
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Out: Thiago Silva (muscle)
Doubtful: Callum Hudson-Odoi (knee)
Crystal Palace
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Out: James McArthur (unspecified), Connor Wickham (unspecified), Wilfried Zaha (thigh), Jeffrey Schlupp (thigh), Mamadou Sakho (thigh), Wayne Hennessey (unspecified), Nathan Ferguson (thigh), James Tomkins (eye), Nathaniel Clyne (muscle)
Doubtful: None
Everton
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Out: Yerry Mina (calf), Jean-Philippe Gbamin (calf)
Doubtful: None
Fulham
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Out: Tom Cairney (knee), Marek Rodak (hand)
Doubtful: None
Leeds United
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Out: Kalvin Phillips (calf), Robin Koch (knee), Rodrigo Moreno (groin), Adam Forshaw (hip), Ian Poveda-Ocampo (ankle), Jamie Shackleton (abductor), Gaetano Berardo (knee)
Doubtful: None
Leicester City
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Out: James Justin (knee), Ayoze Perez (knee), Wesley Fofana (thigh), Dennis Praet (thigh), Wes Morgan (back), James Maddison (groin), Harvey Barnes (knee)
Doubtful: Jamie Vardy (calf), Jonny Evans (calf)
Liverpool
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Out: Jordan Henderson (groin), Joel Matip (ankle), Joe Gomez (knee), Virgil van Dijk (knee), Caoimhin Kelleher (knock)
Doubtful: Alisson Becker (personal), Diogo Jota (knee), Fabinho (muscle)
Manchester City
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Out: Nathan Ake (muscle)
Doubtful: None
Manchester United
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Out: Paul Pogba (thigh), Phil Jones (knee), Juan Mata (unspecified)
Doubtful: Edinson Cavani (muscle)
Newcastle United
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Out: Callum Wilson (hamstring), Javi Manquillo (ankle), Fabian Schar (knee), Allan Saint-Maximin (groin), Miguel Almiron (knee)
Doubtful: Federico Fernandez (thigh), Emil Krafth (knock)
Sheffield United
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Out: John Egan (foot), Sander Berge (thigh), Jack O'Connell (knee), Jack Robinson (unspecified), Chris Basham (muscle), Jayden Bogle (leg), Jack Rodwell (unspecified)
Doubtful: None
Southampton
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Out: Theo Walcott (thigh), Ibrahima Diallo (thigh), Kyle Walker-Peters (hamstring), Michael Obafemi (muscle), Oriol Romeu (ankle), William Smallbone (knee), Takumi Minamino (hamstring)
Doubtful: None
Tottenham Hotspur
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Out: Giovani Lo Celso (thigh)
Doubtful: None
West Bromwich Albion
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Out: Semi Ajayi (suspended), Robert Snodgrass (calf)
Doubtful: Kieran Gibbs (neck)
West Ham United
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Out: Angelo Ogbonna (ankle), Andriy Yarmolenko (knee), Arthur Masuaku (knee)
Doubtful: Ryan Fredericks (groin), Lukasz Fabianski (arm), Darren Randolph (thigh)
Wolverhampton Wanderers
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Out: Raul Jimenez (head), Willy Boly (thigh), Fernando Marcal (muscle), Daniel Podence (adductor)
Doubtful: None