The two East Midlands rivals go head to head at the King Power Stadium while occupying 19th and 20th position in the Premier League standings.
There has been speculation regarding the futures of both managers, most notably Brendan Rodgers with the Foxes bottom of the table after six successive defeats.
However, despite his incredible impact at the City Ground last season, talk regarding an exit for Steve Cooper has also emerged in recent weeks.
The consequences of defeat may lead to, rightly or wrongly, their respective hierarchies acting, particularly in the case of Rodgers.
Still, Forest have posted four defeats in a row in the top flight, conceding as many as 14 goals during setbacks against Tottenham Hotspur, Manchester City, Bournemouth and Fulham.
If Forest lose to Leicester on October 3, it would mark the first time that they have lost five times in succession in the league since January 2004.
On that occasion in the Championship, Forest succumbed to Crystal Palace, Norwich City, West Ham United, Sunderland and Reading without scoring a single goal.
Remarkably, it was part of a 17-game winless streak in the second tier, Forest still finishing in 14th spot in the table after a remarkable impact made by Joe Kinnear from February 10 onwards.
From the perspective of Leicester, Rodgers is looking to avoid losing three home league games in a row for the first time in his career.
Leicester went down by 2-1 and 1-0 scorelines to Southampton and Manchester United before they recently conceded 11 times at Brighton & Hove Albion and Tottenham Hotspur.
Forest will be making their first trip to the King Power Stadium since November 2013, the visitors running out 2-0 victors on that occasion courtesy of goals from Simon Cox and Jamie Mackie.