Pep Guardiola's men are already assured of at least a third-placed finish in the section, having followed up opening wins over RB Leipzig and Red Star Belgrade with a 3-1 triumph over the Swiss outfit at Stadion Wankdorf two weeks ago.
The Citizens also rose to the top of the Premier League table with a 6-1 destruction of Bournemouth in Saturday's Premier League game, where the vivacious Jeremy Doku scored once and set up four more for his new club.
Here, Sports Mole rounds up Man City's latest injury and suspension news ahead of the reunion with Young Boys, who are third in the group with a solitary point to their name.
Erling Haaland
Status: Major doubt
Type of injury: Ankle
Possible return date: November 7 (vs. Young Boys)
Erling Haaland's afternoon against Bournemouth ended prematurely as the Norwegian talisman - who did not contribute to a goal on the day - was withdrawn at half time after twisting his ankle. Guardiola is yet to rule Haaland out of Tuesday's game, but he has conceded that a comeback next weekend against Chelsea might be more realistic.
Kevin De Bruyne
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
City could therefore be without their two prize jewels in the crown this week, as Kevin De Bruyne is still on the road to recovery from a hamstring problem and is expected to miss the remainder of the calendar year.
Sergio Gomez
Status: Out
Type of injury: Unspecified
Possible return date: Unknown
Backup left-back Sergio Gomez was a notable absentee from the squad to take on Bournemouth and was subsequently seen on crutches after apparently picking up an unspecified injury in training, which will seemingly render him unavailable for a while.
MANCHESTER CITY'S SUSPENSION LIST
Manchester City have no suspended players for this match.