The Red Devils have enjoyed their pre-season tour so far, beating Liverpool and Melbourne Victory and scoring four in both games.
United are staying in Australia for another Premier League test against Palace, who have made the trip after a 2-0 loss to Liverpool in Singapore.
Patrick Vieira still has a heavily depleted squad to choose from due to a mixture of fitness and visa issues relating to Melbourne's vaccination rules.
Man United v Crystal Palace: Date and start time
This pre-season friendly will take place on Tuesday, July 19.
Kick-off at the 100,000-capacity Melbourne Cricket Ground in Australia will take place at 11.10am UK time.
United will then travel to Perth to host Aston Villa while Palace will take on Leeds in the same city before returning to London.
Man United v Crystal Palace: TV channel and live stream
The game will again be shown live on MUTV and and PalaceTV.
MUTV costs £7.99 a month while PalaceTV is £4.99 a month and both can be live streamed via the club's websites.
talkSPORT will have regular updates from Melbourne throughout the day while talkSPORT.com will be running a live blog for the action too.
To tune in to talkSPORT or talkSPORT 2 through the website, click HERE for the live stream. You can also listen via the talkSPORT app, on DAB digital radio, through your smart speaker and on 1089 or 1053 AM.
Man United v Crystal Palace: Team news
United are set to welcome back both David de Gea and Raphael Varane after the pair missed the 4-1 win over Melbourne Victory.
Zidane Iqbal and Charlie Savage could once again be afforded minutes but fellow youngsters Hannibal Mejbri and Alejandro Garnacho are yet to play.
Palace, meanwhile, are without the likes of senior stars Marc Guehi, Wilfried Zaha, Eberechi Eze, Michael Olise and Christian Benteke.
In their place, trio Jean-Philippe Mateta, Odsonne Edouard and Jordan Ayew will line-up in attack with Tyrick Mitchell in defence.
Man United v Crystal Palace: What has been said?
"We can't be satisfied anymore with how the team had been going," Luke Shaw said.
"It's not where the club should be and we know the levels have had to take a massive step in terms of higher intensity and what we're supposed to be doing and I think from the start of the last two weeks, especially in training, it's definitely a big improvement.
"And even in the games, I think you could see things that probably you haven't seen before, so I think there are things to look forward to.
"I think the manager knows what the team needs and he has his own style and how he wants to manage and all the players have really taken it on board and they're really enjoying it.
"He is very hands-on and he takes a lot of the sessions. He's involved a lot and if he sees people aren't hitting the standards that he wants in training he'll make sure they know. I think that's good because he keeps the standards high.
"The manager demands more and we have to be better and better. After the first game he said to the press and he also said it to us as well that there were mistakes made that we need to improve on, not just individually but as a team as well.
"He's spoken a lot about the team and the structure and the way he wants to play. It's a lot of details, but details win games and with his philosophy and the way he wants to play, we need to listen.
"It's really good to have an idea of what the manager wants and it's down to us to go and show that on the pitch. And like I said, there is still much more to come from us and this is only the start."