The Reds return to action only four days after booking their place in the Carabao Cup final with a 3-2 aggregate win against Fulham.
Jurgen Klopp's side are one of the most in-form teams in England and the Premier League leaders will be aiming to go all the way in this competition.
That means this will be an tough assignment for the Canaries who were taken to a replay by Bristol Rovers before securing a trip to Merseyside.
Liverpool vs Norwich: Klopp's Best Man
Norwich boss David Wagner will be reunited with one of his closest friends when he arrives at Anfield to take on Klopp's Liverpool.
The German was teammates with the Reds manager at Mainz between 1991 and 1995 as well as the Best Man at his wedding in 2005.
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Speaking after the Canaries progressed, Wagner said: "I haven't checked my messages yet.
"But I wouldn't be surprised if Jurgen has already been in touch now we're through.
"I haven't seen Jurgen in person since his birthday party last year so it will be great to have a bit of reunion with him.
"But it's not about us and above all it's all about making sure my team go to Anfield and do Norwich City proud."
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Liverpool are unbeaten in their last 18 meetings with Norwich in all competitions, since a 1-0 home loss in April 1994 (W16 D2). It's their longest current unbeaten run against any side.
Having won their first three FA Cup games against Liverpool between 1909 and 1951, Norwich have been eliminated from their last three ties against the Reds, most recently in the fifth round in 2021-22.
Liverpool vs Norwich: Team news
Andy Robertson made his long-awaited return to action against Fulham in the Carabao Cup and he should feature in this tie.
Vice-captain Trent Alexander-Arnold could also make a comeback while Dominik Szoboszlai is close to full fitness and may play.
Joel Matip, Konstantinos Tsimikas, Thiago and Stefan Bajcetic all remain out.
As for Norwich, Danny Batth is out while Grant Hanley is carrying a knock that has kept him out of action for the last six games.
Star winger Jonathan Rowe suffered a head injury against Leeds and he is set to be assessed ahead of the trip to Anfield.
Liverpool have progressed from 11 of their last 12 FA Cup ties against teams from a lower division, failing only against Wolves in January 2017 in this run, losing 2-1 at Anfield.
When outside the top-flight themselves, Norwich have been eliminated from their last 12 FA Cup ties against top tier opponents, since a 1-0 win at Stoke City in January 1982.
Liverpool vs Norwich: What has been said?
Wagner is excited for his side to have the opportunity to take on Liverpool this weekend.
He said: "A tie at Anfield is a really big prize for my team and I know my players will relish the opportunity to take on the Premier League's best players.
"But it's not something that should hold any fear for my players and I will be telling them that we will go for it.
"It will be a great game. I promise we will be ready and will give a good account of ourselves."
Liverpool have only won two of their last eight FA Cup home games against sides in the second tier (D2 L4). Indeed, three of their last four home defeats in the competition have been against Championship sides.
Liverpool vs Norwich: talkSPORT coverage
This FA Cup fourth round tie will take place on Sunday, January 28.
Kick-off at Anfield is scheduled for 2:30pm.
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talkSPORT will have live coverage of the game.
Commentary will come from Joe Shennan and former England striker Darren Bent.