While speaking to former player at Chelsea John Obi Mikel, Mourinho was asked who is going to win the Premier League this season.
After taking a moment, The Special One settled on a straight shootout between Liverpool and Manchester City.
He said on The Obi One podcast: "Man City 51 [per cent]. Liverpool 49 [per cent]."
Co-host Chris McHardy was shocked and replied: "No Arsenal?!"
Mourinho's answer was concise but cutting, replying: "Nah."
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Mikel immediately reacted by breaking into fits of laughter at his old manager's assessment before the camera panned back to Mourinho, who was trying to hold in a giggle.
As a former Chelsea and Tottenham manager, it might not be a surprise to see the Portuguese coach not show much support to London rival Arsenal.
However, he did go on to admit he would not mind seeing the Gunners end their two-decade barren spell without a league title.
"Honestly, rivalry apart, I would like them to win," he went on to say.
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"Of course, Chelsea and Man United are not going to win it. Out of these three, I would be happy for Arsenal to do it. I would be really happy for them to break that thing.
"It is because when the accumulation of matches starts coming, Man City have two teams."
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Arsenal came close to winning the Premier League last season but fell short as City triumphed with a run of 12 wins in a row from February onwards.
But Mikel Arteta might fancy his side a bit more this season as they currently sit atop the Premier League table.
While City can never be discounted, they have looked somewhat out of sorts in recent weeks and threw away a two-goal lead against Crystal Palace on Saturday at the Etihad.
It has left them fourth in the league, behind Arsenal, Liverpool and Aston Villa.