The Spurs skipper has been in scintillating form this season, scoring 11 goals and assisting four in 18 Premier League games so far.
However, Ange Postecoglou will have to manage without him over the next few weeks as he travels to Qatar to represent his country.
The Asia Cup begins on January 12 and it means Son could be away for some key fixtures in the top-flight and FA Cup…
How many games will Heung-min Son miss?
Son could miss up to six games for Tottenham in the coming weeks.
South Korea's first game at the Asia Cup is on January 15 but the forward is set to leave to join up with his national team after Spurs' clash with Bournemouth on December 31.
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That means he will definitely be absent for Postecoglou's side's FA Cup third-round tie against Burnley.
He will also miss their huge trip to take on Manchester United at Old Trafford.
Should South Korea reach the latter stages of the competition, Son could then miss a potential FA Cup fourth-round tie.
And he could also be absent for Tottenham's game away at Everton on February 3.
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The Asia Cup final is set to be played on February 10 and if Son reaches the showpiece game, he will miss a sixth match for his club.
Postecoglou would be without his captain when they host Brighton on the same day as the tournament final.
He would then likely return for Tottenham's game against Wolves on February 17.
Speaking about Son leaving to play for his country, the Spurs boss said: "A lot of European people think the Euros are pretty important - well, it's the same for the Asian Cup or the African Cup of Nations."
The Australian then continued, jokingly saying: "I hope Sonny goes on and finishes runner-up to Australia again, mate.
"I'd be really happy about that."