The 31-year-old, who has scored 24 goals for the national team, was an unused substitute for his side's Group D opener against Denmark on Tuesday, which finished 0-0.
Khazri could now be introduced into the XI for this match, with the experienced attacker potentially taking the place of Anis Ben Slimane in the final third of then field.
Tunisia have not reported any injury concerns from their tournament opener, and the manner of the performance would have impressed the manager, so it could be close to the same side for this match.
A 3-4-3 formation should again see Aissa Laidouni and Ellyes Skhiri play in midfield, while Montassar Talbi should retain his spot in a defensive area.
Youssef Msakni is the captain, and the 32-year-old will be bidding to add to his 17 goals for Tunisia in the team's second match of the competition.
Meanwhile, Issam Jebali should also win his 12th cap for the national side in the final third.
Manchester United midfielder Hannibal Mejbri appeared as a substitute against Denmark, and the teenager will be hoping to secure more World Cup minutes here.
Tunisia possible starting lineup: Dahmen; Bronn, Meriah, Talbi; Drager, Skhiri, Laidouni, Abdi; Khazri, Jebali, Msakni