Oliver Glasner's team have made a bright start to 2023 in the Bundesliga, ahead of their return to European action, and an impressive recent run has starred Randal Kolo Muani, who made a name for himself in last year's World Cup.
The French forward leads the line up front, having scored twice in his last two Champions League appearances and seven times in Frankfurt's last six games - including the second in Saturday's victory over Werder Bremen.
It is likely that Glasner will make some changes on Tuesday evening, despite both keeping a clean sheet and denying Werder a single shot on target, and he has an almost full hand available from which to choose as only Eric Dina Ebimbe is set to be sidelined by injury.
After being benched on Saturday, Croatian defender Hrvoje Smolcic could join compatriot Kristijan Jakic in the hosts' back three, while Aurelio Buta may replace Ansgar Knauff out wide.
Danish winger Jesper Lindstrom should start alongside 2014 World Cup-winner Mario Gotze in support of Kolo Muani. Playing in a 'number eight' role, Gotze's career has recently enjoyed a revival and he leads the Bundesliga in terms of distance covered, with 238.6 km run so far this season.
Meanwhile, possibly Barcelona-bound in the summer, Evan N'Dicka features in defence for last year's Europa League winners.
Eintracht Frankfurt possible starting lineup: Trapp; Smolcic, N'Dicka, Tuta; Buta, Kamada, Sow, Max; Lindstrom, Gotze; Kolo Muani