The 21-year-old has netted three times in this year's Champions League and could add to his tally against the Nerazzurri who have found clean sheets hard to come by in recent weeks.
Benfica are one of three unbeaten clubs left in the competition, and they have been aided by an impressive scoring record that is outdone by only Napoli.
Apart from Ramos, the pair of Rafa Silva and Joao Mario have contributed 11 goals and all three of them have netted 14 of the Eagles' 23 strikes in Europe's most prestigious competition.
The injury to Alexander Bah in Friday's O Classico defeat at the hands of Porto may sideline the right-back for the visit of Inter, so Gilberto could replace the 25-year-old Dane from the start.
With Alex Grimaldo's threat from wide positions known, the left-back could cause issues for Inter's backline as he looks to add to his five direct involvements leading to goals in this year's competition, scoring twice and assisting two.
Injuries to Goncalo Guedes, Julian Draxler and Mihailo Ristic rule them out of participation on Tuesday, but they may not have played a dominant part in Lisbon anyway.
Benfica possible starting lineup: Vlachodimos; Gilberto, Silva, Otamendi, Grimaldo; Luis, Chiquinho; Mario, Silva, Aursnes; Ramos