Boyle has been sidelined with a knee injury during Australia's preparations for the first matchday and is yet to train fully with the team, but Graham Arnold should otherwise have everyone fit and raring to go.
Mitchell Duke will expect to spearhead the charge for the Socceroos if Boyle misses out, as Mathew Leckie and Craig Goodwin provide support to the 31-year-old.
Hellas Verona midfielder Ajdin Hrustic has also been training normally recently and could get the nod in a three-man midfield alongside Aaron Mooy and Jackson Irvine here.
However, Stoke City defender Harry Souttar has only played one game for the Potters since recovering from ACL surgery, and a lack of match practice will surely work against him here.
Bailey Wright and Kye Rowles may therefore be preferred at the heart of the backline, while Nathaniel Atkinson and Aziz Behich - who scored an own goal against France at the 2018 World Cup - occupy the full-back roles.
Arnold's decision to bring on Andrew Redmayne for the AFC-CONMEBOL playoff final penalty shootout against Peru was a masterstroke, but Mathew Ryan will unquestionably begin in goal here.
Australia possible starting lineup: Ryan; Atkinson, Wright, Rowles, Behich; Hrustic, Mooy, Irvine; Leckie, Duke, Goodwin