The Blues are coming into this clash after a 2-1 victory over relegation-threatened Leicester City in the Premier League, whilst FCH are aiming to bounce back following a 5-2 thrashing at the home of Bundesliga holders Bayer Leverkusen on the weekend.
Here, Sports Mole rounds up the latest injury news for both Heidenheim and Chelsea ahead of Thursday's clash between two Conference League favourites.
HEIDENHEIM vs. CHELSEA
HEIDENHEIM
Out: Julian Niehues (knee), Luka Janes (shoulder), Marnon-Thomas Busch (groin), Marvin Pieringer (Achilles)
Doubtful: Thomas Leon Keller (lack of fitness)
Sports Mole's predicted XI: Muller; Traore, Manika, Gimber, Fohrenbach; Dorsch, Maloney, Schoppner; Conteh, Honsak, Wanner
CHELSEA
Out: Reece James (hamstring)
Doubtful: Malo Gusto (illness), Levi Colwill (illness), Pedro Neto (knock)
Sports Mole's predicted XI: Jorgensen; Disasi, Badiashile, Adarabioyo, Veiga; Caicedo, George, Nkunku, Felix, Mudryk; Guiu
For data analysis of the most likely results, scorelines and more for this match please click here.