The Blues played their first game after the international break on Saturday, securing a deserved 2-1 victory at Leicester City in the Premier League.
While that remains the priority of Enzo Maresca and his players, Chelsea head into their fixture with their Bundesliga opponents with the realistic possibility of guaranteeing a top-eight spot in the Conference League table with a fourth successive win in the competition.
Here, Sports Mole rounds up Chelsea's latest injury and suspension news ahead of making the trip to Germany.
Pedro Neto
Status: Minor doubt
Type of injury: Unknown
Possible return date: November 28 (vs. Heidenheim)
Neto was a surprise absentee for the Leicester game, Maresca revealing after the game that the Portugal international had "a problem" while representing his country. However, the Italian suggested that the winger is in contention to return on Thursday.
Malo Gusto
Status: Minor doubt
Type of injury: Illness
Possible return date: November 28 (vs. Heidenheim)
Although Gusto had recovered from an ankle knock, he was unavailable against Leicester due to illness. Providing that he is passed fit, the Frenchman could be handed game time at right-back.
Reece James
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
After four successive Premier League appearances, James is again sidelined with a hamstring injury sustained in training. As it stands, the right-back is sidelined for the foreseeable future.
Omari Kellyman
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
Kellyman has struggled with fitness issues since joining the Blues from Aston Villa in the summer; the attacker remains on the sidelines for this match due to a hamstring problem, and it is unclear when he will be able to return.
CHELSEA'S SUSPENSION LIST
Chelsea have no suspension issues heading into this contest. However, Wesley Fofana, Ben Chilwell, Romeo Lavia and Cole Palmer are all ineligible having not been named in the Conference League squad for the League Phase.