The Blues have won just one league game this season and didn't manage to score a single top-flight goal in September.
But they sealed a morale-boosting victory over Brighton at Stamford Bridge in the Carabao Cup last week and will seek to build on that.
Fulham, though, have kept back-to-back clean sheets and won their last home league game 1-0 against Luton Town.
Live commentary: talkSPORT website stream HERE, via the app HERE
Match being broadcast on Sky Sports Main Event and Premier League
Fulham: Leno, Castagne, Diop, Ream, Robinson, Reed, Palhinha, Pereira, Wilson, Jimenez, Willian
Subs: Rodak, Bassey, Decordova-Reid, Cairney, Ballo-Toure, Muniz, Iwobi, Vinicius, Lukic
Chelsea: Sanchez, Disasi, Silva, Colwill, Cucurella, Gallagher, Caicedo, Fernandez, Mudryk, Broja, Palmer
Subs: Petrovic, Sterling, Ugochukwu, Maatsen, Washington, Gilchrist, Brooking, Matos, Madueke
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GOAL! Fulham 0-1 Chelsea - Mykhailo Mudryk
18′ - FINALLY, HE HAS A GOAL
Chelsea move up the field through Colwill.
He looks up and dinks a pass over the top for Mudryk, and he slots in his first top-flight goal.
Murphy: "From the minute I've seen this player, always liked him."
2 minutes ago
Fulham 0-0 Chelsea
17′ - Castagne wins a corner that Pereira takes.
It's flicked on at the near post but Disasi clears.
3 minutes ago
Fulham 0-0 Chelsea
Still thinking about Broja's miss.
4 minutes ago
Fulham 0-0 Chelsea
16′ - Caicedo nicks the ball back from Willian.
The Blues work it to Palmer and he lifts a pass over the top for Broja that Leno gathers.
5 minutes ago
Fulham 0-0 Chelsea
14′ - Fulham are now starting to see more of the ball, but they can't get high up the pitch or close to Sanchez's goal.
Chelsea have got their off-ball shape spot on in the early exchanges.
6 minutes ago
Fulham 0-0 Chelsea
12′ - Gallagher brilliantly spins his man and finds Palmer.
The former Man City man gets the ball back to Gallagher in the box, but he sees Diop clear his shot.
Murphy: "It's been a good start from Chelsea."
8 minutes ago
Fulham 0-0 Chelsea
11′ - The visitors have started well here, but they should be 1-0 through Broja's early sitter.
9 minutes ago
Fulham 0-0 Chelsea
9′ - Palmer cleverly finds Fernandez.
He slips a pass into Mudryk.
The winger cuts in and blasts a wild strike well over the bar.
10 minutes ago
Fulham 0-0 Chelsea
Only Everton (18) have missed more big chances than Chelsea in the Premier League this term (16, alongside Brentford).
11 minutes ago
Fulham 0-0 Chelsea
8′ - Mudryk gets some space on the left as Fernandez feeds him.
He squares up Castagne and just runs the ball out of play.
Murphy: "Its a poor pass from Fernandez but Mudryk has got to do better."
12 minutes ago
Fulham 0-0 Chelsea
7′ - Broja does well to win a free-kick out on the left, which the Blues play back and look to build from Sanchez.
13 minutes ago
Fulham 0-0 Chelsea
5′ - It is indeed Cucurella at right-back.
Colwill continues at left-back, and it's been a decent start from the visitors.
16 minutes ago
Fulham 0-0 Chelsea - Chance
2′ - What an opportunity!
Broja and Gallagher combine.
The striker gets into the box, skips around one man, then goes around the goalkeeper and balloons his shot over the bar.
That was a huge moment!
Murphy: "I thought he's done the hard bit. That was an easy chance."
19 minutes ago
Fulham 0-0 Chelsea - Kick-off
The hosts get us underway kicking from left to right.
21 minutes ago
Fulham vs Chelsea
The hosts are wearing white and black and Chelsea are in their traditional all blue.
24 minutes ago
Fulham vs Chelsea
Here come the players, with Tim Robinson leading out both sets of teams.
25 minutes ago
Fulham vs Chelsea
The teams are in the tunnel…
26 minutes ago
Fulham vs Chelsea
Not long to go now before we get underway under the lights.
29 minutes ago
Fulham vs Chelsea
Hopefully, we get some goals this evening, but these two are the joint second-lowest scorers in the Premier League.
Both sides have just five each.
Surely, that will all change this evening?
31 minutes ago
Fulham vs Chelsea
Marco Silva wants his team to keep grafting for the badge and for the club in an effort to turn Craven Cottage into a fortress.
Speaking to Sky Sports, he said: "We have to keep working hard.
"We have to respect ourselves, be ambitious and understand the league.
"We have to be humble to understand we are facing Chelsea, but our focus is ourselves.
"Every time we play at home, it's always a good chance for us to go and win the game."
34 minutes ago
Fulham vs Chelsea
Cottagers boss Marco Silva has been speaking to Sky Sports about the upcoming test this evening.
He said: "Last season, we were brave and played with courage and quality, and we did really well.
"These are the characteristics that I always want to see from my players and in my team.
"We need to be brave and play in the way we want with a plan, and to be aggressive on and off the ball."
37 minutes ago
Fulham vs Chelsea
Raheem Sterling isn't fit enough to start this evening.
But he has still been talking to his teammates in the warm-up in an effort to get them fired up.
39 minutes ago
Fulham vs Chelsea
It's a big night for Armando Broja.
Broja is making his first Premier League start for Chelsea since November 2022 (a 1-0 loss at Newcastle), 324 days ago.
He has failed to score in his last 13 Premier League starts, after netting six goals across his first 11 starts in the competition.
43 minutes ago
Fulham vs Chelsea
The folks at British Gambler have put together some data that shows that Chelsea have the lowest win percentage of the 17 teams that have played both seasons in 2023.
You have to remember how much the Blues have spent this year alone.
48 minutes ago
Fulham vs Chelsea
What a great team we have for you this evening!
Adrian Durham is your host and commentary is coming from Sam Matterface and Danny Murphy.
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