The Blues head into the fixture having been held to a goalless draw by Everton in their latest encounter in the Premier League.
As a result, Chelsea sit four points adrift of leaders Liverpool in the standings ahead of facing a team in Fulham who were also involved in a stalemate at the weekend.
Here, Sports Mole rounds up Chelsea's injury and suspension news ahead of welcoming their West London neighbours down the King's Road.
Wesley Fofana
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
After sustaining a hamstring injury in the win over Aston Villa at the start of the month, it was revealed Fofana will spend four-to-five weeks on the sidelines. As it stands, the Frenchman is still working his way back to fitness.
Reece James
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
Another hamstring injury for James means that he is currently on the treatment table. However, while no date has been pencilled in for his return, the Englishman is back on the training pitch.
Benoit Badiashile
Status: Out
Type of injury: Unknown
Possible return date: Unknown
Maresca revealed that Badiashile picked up an injury in training ahead of the fixture with Brentford. He has since stated that he will be "out for a long period", indicating that it will be 2025 before the Frenchman is available again.
Omari Kellyman
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
Summer signing Kellyman has missed the entirety of the season so far for the Blues, and will not return until the new year at the earliest due to a hamstring injury of his own.
Romeo Lavia
Status: Major doubt
Type of injury: Muscle
Possible return date: Boxing Day (vs. Everton)
Lavia has been unavailable for the last two Premier League fixtures due to what is believed to be a minor issue. However, the Belgium international is seemingly closing in on a return to fitness for the upcoming derby fixture.
CHELSEA'S SUSPENSION LIST
Chelsea have no suspension issues heading into this game.
Written by
Darren Plant