Thomas Tuchel's Blues finished third in the Premier League last term and were beaten by Liverpool in both the FA Cup and Carabao Cup finals.
The west Londoners will be eager to improve this season and will kick-off their preparations in earnest in the USA.
Chelsea will face Arsenal in Orlando later this month but first take on Club America and Charlotte FC.
The Premier League giants are in Sin City first and will be keen to get their tour off to a good start.
Chelsea v Club America: Date and start time
This pre-season friendly will take place on Sunday, July 17.
The match is being held at the 65,000-capacity Allegiant Stadium in Las Vegas.
It will kick-off at 3am UK time.
Chelsea v Club America: TV channel and live stream
This pre-season tie will be broadcast live on Chelsea's website and their 'The 5th Stand' app.
talkSPORT will have regular updates from the USA throughout the day while talkSPORT.com will have reaction to the tie too.
To tune in to talkSPORT or talkSPORT 2 through the website, click HERE for the live stream. You can also listen via the talkSPORT app, on DAB digital radio, through your smart speaker and on 1089 or 1053 AM.
Chelsea v Club America: Team news
N'Golo Kante and Ruben Loftus-Cheek have not travelled due to their Covid vaccination status while Armando Broja has stayed at home too amid speculation over his future.
Conor Gallagher, Billy Gilmour and Michy Batshuayi are among the players who were on loan last season but are now back with the Blues.
Goalkeepers: Kepa Arrizabalaga, Marcus Bettinelli, Edouard Mendy, Teddy Sharman-Lowe
Defenders: Marcos Alonso, Ethan Ampadu, Cesar Azpilicueta, Trevoh Chalobah, Ben Chilwell, Levi Colwill, Reece James, Kenedy, Emerson Palmieri, Malang Sarr, Thiago Silva
Midfielders: Ross Barkley, Conor Gallagher, Billy Gilmour, Jorginho, Mateo Kovacic, Mason Mount, Harvey Vale
Forwards: Tino Anjorin, Michy Batshuayi, Kai Havertz, Callum Hudson-Odoi, Christian Pulisic, Timo Werner, Hakim Ziyech
Chelsea v Club America: What has been said?
Chelsea star Mason Mount: "It's only been three weeks off so you don't lose too much, and I always like to keep ticking over a little bit by doing training. In Portugal, with Chelsea Under-23s when they were there, I joined in a little shooting drill with them.
"When you keep ticking over it helps when you first come back to not feel too far behind. There's been a group that have come back before us and been training for the past week so they are in good form.
"I was just buzzing to get back with the boys, to get back with all the staff, to really get back working hard and get the season running. We've got a good few games here in America, a great few weeks, so we'll enjoy it.
"I would never set a target of winning Player of the Year. I set targets for what I want to achieve goals-wise, assists-wise, competitive-wise as a team.
"If I reach those targets then I know that my level is going to be high and I'm going to be performing. That's what I look at and when I sit down before a season and try to set my targets, I want to achieve more. That's always been my goal and my focus before a season."