The club are currently rock bottom of the league and the supporters have had enough.
Puel risked the fury of the fans when he said he was under 'no pressure' just one day before the game.
He said: "I think the supporters will get behind their team and that's the most important thing.
"We're at home and we must impose pressure on our opponents and not have an atmosphere that undermines our team.
"For me there's no pressure. I'm entirely focused on what we have to do and how to get the team to perform."
Fans responded by putting a banner outside the training ground telling the former Leicester boss he had just 24 hours to resign.
A day later and Puel was still in charge of the club and the supporters were furious.
They unveiled a banner that read: "We've had enough talk, you're making us crack."
Flares rained down on the pitch just before kick-off and the game could not start.
The players were taken back down the tunnel, with pictures showing riot police guarding the entrance to stop any supporters from confronting the manager.
The game did eventually get underway at around 9pm, but things went from bad to worse.
Angers took the lead after 29 minutes, with it looking like another poor night for the French club.