The Indomitable Lions came back from two goals down to secure a 3-3 draw with Serbia in one of the games of the tournament, but they will need to be even better against Tite's men.
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Brazil have already qualified for the last 16 after wins over Serbia and Switzerland, so they could rotate and will be without Neymar.
The tournament favourites are yet to concede a shot on target at the World Cup, so it's going to be a tough game for Cameroon.
But they will be buoyed by their performance in the last clash and will hope they can follow Saudi Arabia and Japan and earn a shock win over a top nation.
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Cameroon v Brazil: talkSPORT coverage
This Group G World Cup clash will take place on Friday, December 2.
The match at the Lusail Iconic Stadium in Lusail will kick-off at 7pm UK time.
talkSPORT will have full coverage of the clash and commentary will come from Adrian Durham, Jim Proudfoot and former England defender Stuart Pearce.
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Cameroon v Brazil: Squads and team news
The Indomitable Lions will be without Inter Milan goalkeeper Andre Onana for the rest of the tournament after falling out with boss Rigobert Song.
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Onana has left the squad and Devis Epassy is likely to keep his place in goal ahead of Simon Ngapandouetnbu.
Meanwhile, Vincent Aboubakar will hope to make the starting XI after his game-defining cameo against Serbia.
Brazill will be without Neymar and Danilo, while there could be more rotation as Antony, Gabriel Jesus and Bruno Guimaraes all push for starts.
Brazil
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Goalkeepers: Alisson, Ederson, Weverton
Defenders: Dani Alves, Danilo, Alex Sandro, Alex Telles, Bremer, Eder Militao, Marquinhos, Thiago Silva
Midfielders: Bruno Guimaraes, Casemiro, Everton Ribeiro, Fabinho, Fred, Lucas Paqueta
Forwards: Antony, Gabriel Jesus, Gabriel Martinelli, Neymar, Pedro, Raphinha, Richarlison, Rodrygo, Vinicius Jr
Cameroon
Goalkeepers: Devis Epassy, Simon Ngapandouetnbu
Defenders: Jean-Charles Castelletto, Enzo Ebosse, Collins Fai, Olivier Mbaizo, Nicolas Nkoulou, Tolo Nouhou, Christopher Wooh
Midfielders: Martin Hongla, Pierre Kunde, Olivier Ntcham, Gael Ondoua, Samuel Oum Gouet, Andre-Frank Zambo Anguissa
Forwards: Vincent Aboubakar, Christian Bassogog, Eric Maxim Choupo-Moting, Souaibou Marou, Bryan Mbeumo, Nicolas Moumi Ngamaleu, Jerome Ngom, Georges-Kevin Nkoudou, Jean-Pierre Nsame, Karl Toko Ekambi
Cameroon v Brazil: Match facts
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Brazil have won five of their six meetings with Cameroon in all competitions (L1), most recently a 1-0 friendly win in November 2018. Brazil have won both previous FIFA World Cup games between the sides, 3-0 in 1994 and 4-1 in 2014.
Cameroon's first ever FIFA World Cup game (Peru in 1982) and first ever FIFA World Cup victory (Argentina in 1990) came against South American opponents. Overall they've won two, drawn two and lost two of their World Cup games against such sides, with both defeats coming against Brazil.
Brazil have won all seven of their FIFA World Cup matches against African sides, scoring 20 goals and conceding just twice.
A defeat or draw for Cameroon will see them eliminated from the group stages of the World Cup in their sixth successive appearance at the finals, last reaching the knockout rounds in 1990. They've never won their final group stage game in seven previous appearances at the World Cup (D2 L5).
Brazil are yet to face a single shot on target at the 2022 World Cup, the first team to not face a shot on target in their first two games at a tournament since France in 1998. The fewest shots on target faced by a team in a group stage since 1966 is two by Argentina in 1998.
Having kept a clean sheet in three of their first four World Cup games, Cameroon have kept just one in their subsequent 21 matches in the competition (46 goals conceded). Their 3-3 draw with Serbia last time out was the first time they've ever scored three goals in a single World Cup match.
Brazil are unbeaten in their last 17 World Cup group stage matches (W14 D3), a tournament record. They are looking to win all three of their group matches at a single edition for the first time since 2006.
Brazil have kept a clean sheet in five of their last six World Cup matches, failing only in their 2-1 quarter-final defeat to Belgium in 2018. They'd only kept four clean sheets in their previous 16 games before this run.
Last time out against Serbia, Cameroon's Vincent Aboubakar became the first substitute to both score and assist a goal in a World Cup match for an African nation. His goal involvements pulled Cameroon from 3-1 down to 3-3 just 11 minutes after he'd come off the bench.
Through the first two rounds of group games at the 2022 World Cup, only Kylian Mbappé (23) was involved in more open play sequences that ended with a shot than Brazil's Vinícius Júnior (15). In the same period, only Mbappé and Ismaïla Sarr (four each) created more chances following a carry than the Brazilian (3).