The Catalan outfit missed the chance to move to the summit on Thursday as they suffered a surprise 2-1 home defeat to Granada.
Ronald Koeman's side are currently third in the table, two points behind leaders Atletico Madrid ahead of their home fixture against the capital outfit next weekend.
Here, Sports Mole rounds up all of Barca's latest injury and suspension news ahead of their clash with Los Che.
Ansu Fati
Status: Out
Type of injury: Knee
Possible return date: Unknown
Ansu Fati is still recovering from the serious knee injury that he sustained in November, and it is unclear when the highly-rated youngster will be able to return to the field.
Philippe Coutinho
Status: Out
Type of injury: Knee
Possible return date: Unknown
Philippe Coutinho, who is currently being linked with a move to Everton, is yet to feature in 2021 due to the knee injury that he suffered against Eibar in December. The Brazilian will also miss out this weekend, and it seems unlikely that he will return before the end of the campaign.
Martin Braithwaite
Status: Major doubt
Type of injury: Ankle
Possible return date: May 2 (vs. Valencia)
Martin Braithwaite has now missed Barca's last three league matches with an ankle problem, and the Denmark international remains a major doubt for this weekend's contest at Mestalla.
BARCELONA'S SUSPENSION LIST
Barca have no players suspended for this match.