The Red Devils are winless in four and most recently drew 3-3 with Porto in the Europa League, while the Lions earned a famous 1-0 win over Bayern Munich in the Champions League, and here Sports Mole rounds up the team news for both clubs.
ASTON VILLA vs. MANCHESTER UNITED
ASTON VILLA
Out: Tyrone Mings (knee), Boubacar Kamara (knee), John McGinn (thigh)
Doubtful: Amadou Onana (hamstring), Jacob Ramsey (groin), Leon Bailey (fitness)
Sports Mole's predicted XI: Martinez; Konsa, Carlos, Torres, Digne; Rogers, Barkley, Tielemans, Philogene; Duran, Watkins
MANCHESTER UNITED
Out: Luke Shaw (calf), Tyrell Malacia (knee), Leny Yoro (foot)
Doubtful: Mason Mount (knock), Kobbie Mainoo (knock)
Sports Mole's predicted XI: Onana; Mazraoui, De Ligt, Maguire, Dalot; Eriksen, Ugarte; Garnacho, Fernandes, Rashford; Zirkzee
For data analysis of the most likely results, scorelines and more for this match please click here.