The 25-year-old arrived in Turin two years ago as part of a move which saw Miralem Pjanic head in the opposite direction, but the transfer has not worked out as intended for either man.
Pjanic has been frozen out of the squad at Barcelona, and Arthur could be part of a mass midfield exodus at Juventus after struggling to fulfil his potential under Massimiliano Allegri.
Arthur has only registered one goal and one assist from 63 games in a Juventus jersey and made 20 Serie A appearances last term without a goal contribution - starting 11 of them.
The Brazil international is still under contract with the Old Lady until 2025, but Arsenal appear to have reignited their interest in a deal for the out-of-favour midfielder.
According to reports in Italy - via the Daily Express - Arsenal and Juventus are making progress in negotiations over a deal for Arthur and have already come to an agreement of sorts.
The Gunners have allegedly agreed to take Arthur on loan with an obligation to buy at the end of the season, and the midfielder has been left out of Allegri's squad for Juve's pre-season trip to the USA.
As well as Arthur, Juventus are also expected to offload the duo of Adrien Rabiot - who is understood to be in talks with Lyon - and ex-Arsenal midfielder Aaron Ramsey.
Weston McKennie has also been linked with a move to Tottenham Hotspur, but Allegri may be forced to shelve plans to offload the £34m-rated American after Paul Pogba's injury.
The former Manchester United man sustained a meniscus issue in training in Los Angeles, and there are now concerns that he could miss the next two months while he recovers from potential surgery.
Arsenal are known to be in the market for midfield reinforcements this summer, despite already signing Fabio Vieira and tying Mohamed Elneny down to a new one-year contract.
New recruit Oleksandr Zinchenko is also capable of featuring in the engine room, but Mikel Arteta has emphasised that he primarily views the 25-year-old as a left-back.
The Gunners are yet to make an offer for Leicester City's Youri Tielemans, who is now thought to be increasingly likely to remain at the King Power for the 2022-23 campaign.
Lucas Torreira has been involved in Arsenal's pre-season after returning from his loan spell at Fiorentina, but the Uruguay international has already confirmed that he wants to leave the Gunners this summer.
Torreira's agent has revealed that a pre-contract agreement is in place with Valencia, but the 26-year-old was nevertheless involved in Arsenal's pre-season tour of the USA earlier this month.