The Red Devils' new head coach has failed to hit the ground running since his appointment in November, and things went from bad to worse as his side fell to a 2-0 defeat to Wolves on Boxing Day.
This was United's third defeat in a row, with all three coming in the space of a week, meaning that Amorim has now lost five of his opening ten games in charge at Old Trafford.
With four of these defeats coming in the league, the 39-year-old has reached this figure in just his seventh league match in charge, faster than any United boss in Premier League history.
Given the £9.2million the English giants paid to former employers Sporting Lisbon to bring Amorim to the club, these statistics are far from ideal.
In the time since his arrival, United have axed sporting director Dan Ashworth sacked just 159 days into the job, while Amorim's replacement at Sporting, Joao Pereira, was fired after eight games in charge on Christmas Day.
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And the Portuguese coach has admitted that he is fully aware of the cut-throat nature of management at the highest level.
Speaking after his side's defeat to Wolves, he said: "I know the business that I'm in.
"The manager of Manchester United can never, no matter what, be comfortable.
"I know that if we don't win, regardless, if they pay the buyout or not, I know that every manager is in danger. I like that because that is the job, so I understand the question.
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"You can argue that I have been here one month and I've had four training (sessions), but we are not winning. That is the reality and I'm quite comfortable with that."
Defeat at Molineux saw the Red Devils booed by their supporters at the final whistle, with their side currently languishing in 14th position in the league table.
And while Amorim said that he was aware of the challenges facing him when he stepped into the job, he confessed that he hadn't expected to find results so hard to come by.
He continued: "There's no point talking about that or thinking about that [being sacked]. I'm here and have to focus on the job.
"It's part of football to have these difficult moments. I already knew that was going to be tough.
"You expect to win more games, to have players with more confidence to sell the idea and to work and improve things. At this moment it's really hard.
"We have to survive to have time and then to improve the team."
United face another difficult taste when they host high-flying Newcastle on Monday night.
The Magpies are currently fifth in the Premier League table, and have won their last four matches in all competitions.
And despite Amorim's commitment to turning things around at Old Trafford, he admitted to talkSPORT that it could be some time before supporters begin to see an improvement.
The former Sporting boss said: "I said it to everybody, this will be a long journey, and this moment will be really tough.
"And we are not near that moment [being back in form]."