The Citizens have this final league game to cross off before switching full focus to next week's Champions League final, while Everton have plenty to play for as they remain in contention for a European spot.
Here, Sports Mole rounds up all of the latest team news for the two clubs.
MANCHESTER CITY vs. EVERTON
MANCHESTER CITY
Out: Joao Cancelo (suspended)
Doubtful: Ilkay Gundogan (knock), Sergio Aguero (adductor), Kevin De Bruyne (fitness)
Sports Mole's predicted XI: Ederson; Walker, Laporte, Ake, Mendy; De Bruyne, Fernandinho, Rodrigo; Torres, Aguero, Sterling
EVERTON
Out: Jean-Philippe Gbamin (knee)
Doubtful: James Rodriguez (knock)
Sports Mole's predicted XI: Pickford; Godfrey, Mina, Keane, Digne; Coleman, Doucoure, Allan, Sigurdsson; Richarlison, Calvert-Lewin
Video prediction
Watch the Sports Mole Football Shorts prediction for this game below: