Mallorca vs. Las Palmas (Saturday, 1.00pm)
Mallorca will be looking to give their La Liga survival hopes a huge boost when they welcome Las Palmas to Estadi Mallorca Son Moix on Saturday afternoon.
The home side are currently 17th in the table, six points above 18th-placed Cadiz, while Las Palmas, who are on a seven-game losing run in Spain's top flight, occupy 14th spot.
We say: Mallorca 1-0 Las Palmas
Granada's relegation could be confirmed early on Saturday afternoon, as we are backing Mallorca to claim a narrow win over Las Palmas. The reverse clash earlier this season finished 1-1, but Las Palmas are in such disappointing form, and we can see another loss for Pio Pio this weekend.
Villarreal vs. Sevilla (Saturday, 3.15pm)
Sevilla will be bidding to continue their excellent run of form when they head to Estadio de la Ceramica on Saturday afternoon to take on Villarreal.
The visitors are 12th in the table, picking up 41 points from their 34 league matches this season, while Villarreal occupy ninth, four points above their opponents in this weekend's contest.
We say: Villarreal 1-1 Sevilla
As mentioned, three of the last four meetings between these two sides in Spain's top flight have finished all square, and we are expecting another draw here. There is not an awful lot between the teams when it comes to quality, and neither would be too disappointed with a share of the spoils on Saturday.
Granada vs. Real Madrid (Saturday, 5.30pm)
Newly-crowned La Liga champions Real Madrid will be looking to record their 28th league victory of the campaign when they head to relegation-threatened Granada on Saturday night.
Real Madrid secured the title with four games to spare last weekend, while Granada are fighting for their lives, and their relegation back to the Segunda Division could be confirmed ahead of this match.
We say: Granada 1-3 Real Madrid
Real Madrid will not be at full strength, but we are still expecting the champions to be too much for Granada. We have tipped Mallorca to beat Las Palmas, so Granada's relegation could be confirmed ahead of this match, and the hosts are unlikely to be able to pick up a positive result against Ancelotti's team.
> How Real Madrid could line up against Granada
> Real Madrid injury update vs. Granada - Aurelien Tchouameni return date
Athletic Bilbao vs. Osasuna (Saturday, 8.00pm)
Athletic Bilbao will be bidding to remain in the hunt for a top-four position in La Liga when they welcome Osasuna to San Mames on Saturday night.
Ernesto Valverde's side are fifth in the table, six points behind fourth-placed Atletico Madrid, while Osasuna occupy 13th spot, boasting 39 points from their 34 league matches this season.
We say: Athletic Bilbao 2-1 Osasuna
Both sides have selection issues ahead of this match, and it has the potential to be a very tricky match for Athletic, who will have a patched-up defence. The Basque outfit need to win to stay in the top-four race, though, and we are backing them to navigate their way to an important three points.