The Maroon became the first host nation to lose their opening World Cup game as Enner Valencia struck twice to hand Ecuador a 2-0 victory when the sides squared off in Group A on Sunday.
Meanwhile, Senegal were denied a dream start to the tournament as they suffered a 2-0 loss against Netherlands on Monday courtesy of late goals from Cody Gakpo and Davy Klaassen.
Here, Sports Mole looks at how the squads of Qatar and Senegal stack up against each other ahead of Friday's matchup.
QATAR
Most valuable player:
Akram Afif (£3.5m)
Overall squad value:
£13m
Most capped player:
Hassan Al-Haydos (170)
Leading goalscorer:
Almoez Ali (42)
Total caps:
1,485
Total goals:
192
Oldest player:
Abdulaziz Hatem (32)
Youngest player:
Jassem Jaber (20)
Average age:
27
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Goalkeepers: Saad Al Sheeb (Al Sadd), Mishaal Barshim (Al Sadd), Youssef Hassan (Al-Gharafa)
Defenders: Ro-Ro (Al-Sadd), Abdul Karim Hassan (Al-Sadd), Tariq Salman (Al-Sadd), Musab Khader (Al-Sadd), Homam Ahmed (Al-Gharafa), Bassam Al-Rawi (Al-Duhail), Boualem Khoukhi (Al-Sadd), Jassem Jaber (Al-Arabi), Ismaeel Muhammad (Al-Duhail)
Midfielders: Abdulaziz Hatem (Al-Rayyan), Muhammad Waad (Al Sadd), Ali Assadalla (Al Sadd), Salem Al Hajri (Al Sadd), Karim Boudiaf (Al-Duhail), Assim Madibo (Al-Duhail), Mustafa Tarek (Al Sadd)
Forwards: Akram Afif (Al Sadd), Ahmed Alaaeldin (Al-Gharafa), Mohammed Muntari (Al-Duhail), Hassan Al-Haydos (Al Sadd), Khalid Muneer (Al-Wakra), Almoez Ali (Al-Duhail), Naif Al-Hadhrami (Al-Rayyan)
SENEGAL
Most valuable player:
Kalidou Koulibaly (£30.4m)
Overall squad value:
£199.3m
Most capped player:
Idrissa Gueye (97)
Leading goalscorer:
Ismaila Sarr & Famara Diedhiou (10)
Total caps:
558
Total goals:
39
Oldest player:
Idrissa Gueye (33)
Youngest player:
Pape Matar Sarr (20)
Average age:
25.9
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Goalkeepers: Edouard Mendy (Chelsea), Alfred Gomis (Rennes), Seny Dieng (Queens Park Rangers)
Defenders: Kalidou Koulibaly (Chelsea), Fode Ballo-Toure (AC Milan), Pape Abou Cisse (Olympiacos), Youssouf Sabaly (Real Betis), Ismail Jakobs (Monaco), Formose Mendy (Amiens), Abdou Diallo (RB Leipzig), Moussa N'Diaye (Anderlecht)
Midfielders: Idrissa Gueye (Everton), Nampalys Mendy (Leicester City), Cheikhou Kouyate (Nottingham Forest), Pathe Ciss (Rayo Vallecano), Krepin Diatta (Monaco), Pape Matar Sarr (Tottenham Hotspur), Moustapha Name (Pafos), Mamadou Loum (Reading), Pape Gueye (Marseille)
Forwards: Nicolas Jackson (Villarreal), Boulaye Dia (Salernitana), Ismaila Sarr (Watford), Famara Diedhiou (Alanyaspor), Bamba Dieng (Marseille), Iliman Ndiaye (Sheffield United)
Read more on Qatar vs Senegal
Click here to read our full preview for Qatar vs Senegal
How Qatar could line up against Senegal
How Senegal could line up against Qatar
Read more on Qatar vs Senegal
Click here to read our full preview for Qatar vs Senegal
How Qatar could line up against Senegal
How Senegal could line up against Qatar