Julen Lopetegui's side lost to Osasuna last weekend, while their visitors were beaten by Villarreal on their return to Spain's top flight.
Match preview
After maintaining a title push for large portions of last season, only narrowly trailing Real Madrid for the majority of the term, Sevilla ended on a disappointing note, eventually dropping to fourth place.
Having also dropped out of the Europa League in the round-of-16, Los Hispalenses were, at least, able to keep their place in the top four and book a spot in the upcoming Champions League group stage as they finished a point behind third-placed Atletico Madrid and three behind second-placed Barcelona.
Turning their attention to the new campaign, they had a mixed run of results in pre-season, drawing with Tottenham Hotspur and Sporting Lisbon and beating Angers and Cadiz while also losing to Leicester City and suffering a 6-0 thrashing at the hands of Arsenal in the Emirates Cup final.
Sevilla's league season began with a trip to Osasuna last Friday, and Rafa Mir quickly drew them level after Ezequiel Avila's early opener, only for the hosts to snatch all three points in the 74th minute as Aimar Oroz converted a penalty.
With their sights set on again pushing at the top end of the table this term, Lopetegui's men will be desperate to ensure they put their first points on the board on Friday and kickstart a positive run of form.
They welcome a Real Valladolid side also looking for their first points amid a tough opening schedule following their promotion back to the top flight.
After dropping out of La Liga in the 2020-21 campaign, The Blanquivioletas kept themselves in the fight for promotion throughout last term but looked confined to the playoffs with a five-point gap to bridge to the top two with just four games to go.
Pacheta's side were able to sneak into the automatic promotion spots on the final day, though, beating then-second-placed Huesca 3-0 in the decider to make it four straight wins as Shon Weissman, Gonzalo Plata and Alvaro Aguado got on the scoresheet at the Estadio Jose Zorrilla.
Following a positive pre-season campaign, culminating in a draw with Lazio and a penalty shootout win, the Blanquivioletas began the La Liga term with a clash again Villarreal, and, after Pacheta's men kept the contest goalless in the first half, their visitors eventually took a lead through Nicolas Jackson, before Alex Baena wrapped up all three points with a late brace.
Hoping to establish themselves in the top flight in the coming seasons, Real Valladolid will be keen to quickly get their points tally up and running to avoid being cut adrift at the bottom of the table as the league continues, but they face another tough test away at the top-four hopefuls.
Sevilla La Liga form:
Real Valladolid La Liga form:
Team News
Sevilla will likely remain without wingers Suso and Munir El-Haddadi, after they missed the opening-day clash with Osasuna due to injuries, while Karim Rekik and Nemanja Gudelj will play in the middle of the back four after Jules Kounde and Diego Carlos both departed over the summer.
Lopetegui still has options to choose from though, with Jesus Corona, Lucas Ocampos, Alejandro Gomez and Erik Lamela all vying to feature behind a lone striker, with Rafa Mir preferred over Youssef En-Nesyri at the top end of the pitch last time out.
Left-back Alex Telles featured off the bench last week, and the Manchester United loanee will hope for a first competitive start in place of Marcos Acuna, while Joan Jordan and Ivan Rakitic are also vying to come into the starting XI after Fernando and Thomas Delaney were deployed in the engine room against Osasuna.
Real Valladolid's only absentee should be star forward Shon Weissman, who hit 20 league goals last season and is continuing a recovery from an injury.
As a result, Sergio Leon should keep his place up front, with Gonzalo Plata and Toni Villa again set to play on the wings.
Pacheta added La Liga experience to his squad over the summer with the signing of Villarreal goalkeeper Sergio Asenjo, and the 33-year-old will continue to operate between the sticks, while Sergio Escudero has also arrived to bolster the defensive ranks and will play against the club he made 176 appearances for between 2015 and 2021.
Sevilla possible starting lineup:
Bono; Navas, Rekik, Gudelj, Acuna; Fernando, Rakitic; Corona, Gomez, Ocampos; Mir
Real Valladolid possible starting lineup:
Asenjo; Perez, Fernandez, Yamiq, Escudero; Mesa, Monchu, Aguado; Plata, Leon, Villa